Synthesis of heme - Study guides, Class notes & Summaries

AAB MT Hematology | Questions and Correct Answers | Latest Update 2024/2025 | 100% PASS What is hemoglobin composed of? - Answer -4 heme, 4 iron, 4 globins What disorder does a defect in heme synthesis lead to? - Answer - Porphyria Porphyria - Answer -Deficiency in the enzymes of the porphyrin pathway leads to insufficient production of heme. The principal problem in these deficiencies is the accumulation of porphyrins, the heme precursors, which are toxic to tissue in high concentrati...

Porphyrin correct answer: Cyclic molecules formed by the linkage of 4 pyrole rings through methynl bridges. They bind metals tightly Name the 4 physiological roles of the HEME porphoryin correct answer: 1. Mitochondrial cytochrome: generate H+ gradient in ETC 2. Hemoglobin and Myoglobin: O2 transport in blood and muscle 3. Cytochrome P450 enzymes: metabolize fat soluble compounds. (CYP3A4) important in drug reactions 4. Catalase: antioxidant enzyme hydrolyzes H2O2 Where is Heme made...

Protons are pumped by mitochondria during active electron transport correct answers outside the inner mitochondrial membrane. As electrons from NADH pass through the electron transport system, correct answers protons are pumped across the mitochondrial membrane to create a pH gradient. The first enzyme in the electron transport system is referred to as complex I, otherwise known as correct answers NADH-ubiquinone oxidoreductase. Which statement is true of the mitochondrial electron tran...

The light-colored zone adjacent to the nucleus in a plasmacyte is the: A. ribosome B. chromatin C. mitochondria D. Golgi area - D. Golgi area The majority of the iron in an adult is found as a constituent of: A. hemoglobin B. hemosiderin C. myoglobin D. transferrin - A. hemoglobin The main function of the hexose monophosphate shunt in the erythrocyte is to: A. reglate the level of 2,3-DPG B. provide reduced glutathione to prevent oxidation of hemoglobin C. prevent the reduction of h...

Protons are pumped by mitochondria during active electron transport correct answers outside the inner mitochondrial membrane. As electrons from NADH pass through the electron transport system, correct answers protons are pumped across the mitochondrial membrane to create a pH gradient. The first enzyme in the electron transport system is referred to as complex I, otherwise known as correct answers NADH-ubiquinone oxidoreductase. Which statement is true of the mitochondrial electron tran...

What is hemoglobin composed of? - correct answer 4 heme, 4 iron, 4 globins What disorder does a defect in heme synthesis lead to? - correct answer porphyria What is the function of the enzyme methemoglobin-cytochrome C reductase in a red blood cell? - correct answer to keep iron in the ferrous state Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than oxygen? - correct answer carboxyhemoglobin What product is formed when ferrous iron of h...

USMLE STEP 1 - UWORLD HIGH YIELD EXAM | QUESTIONS AND ANSWERS | 2024 What are the two major microtubular motor proteins? Which does anterograde axonal transport, which does retrograde axonal transport? - Kinesin, Dynein Kinesin: Anterograde Dynein: Retrograde` What do you think, immunologically speaking, when you see someone with recurrent Neisseria infections? - Inability to form the membrane attack (MAC) complex this is a common complement deficiency What is the defect in...

Serum Albumin - 3.5-5.0 g/dl visceral protein maintains colloidal osmotic pressure hypoalbumiemia associated with edema, surgery levels above range likely do to dehydration long half-life, doesn't reflect current protein intake Serum Transferrin - >200 mg/dl visceral protein that transports iron to bone marrow for production of hemoglobin. serum levels controlled by iron storage pool levels rise with iron deficiency. transferrin synthesis can be determined by TIBC= total iron bi...

Mr. Smith moved from a low altitude to a high altitude and experienced an increase in RBCs. Which of the following caused this increase? Select one: a. The lower temperature present at higher altitudes b. The lower O2 concentration seen at higher altitudes c. The increased CO2 retention that occurs at high altitudes d. The increased metabolic rate seen at higher altitudes e. Increased exercise Question 2 Correct 4.00 points out of 4.00 Flag question Question text Aspirin inhibits pl...

USMLE Step 1 - uWorld High Yield Notes with 100% Correct Score What are the two major microtubular motor proteins? Which does anterograde axonal transport, which does retrograde axonal transport? - Correct Answer ️️ -Kinesin, Dynein Kinesin: Anterograde Dynein: Retrograde` What do you think, immunologically speaking, when you see someone with recurrent Neisseria infections? - Correct Answer ️️ -Inability to form the membrane attack (MAC) complex this is a common complement defi...