Amide local anesthetics - Study guides, Class notes & Summaries

Table of content. Chapter Pages (1) GENERAL PRINCIPLES OF PHARMACOLOGY Error! Bookmark not defined. PART I PHARMACOKINETICS 4 PART II PHARMACODYNAMICS 8 (2) AGENTS, CONTROLLING THE FUNCTIONS OF THE PERIPHERAL NERVOUS SYSTEM 14 PART I LOCAL ANESTHETICS 14 PART II CHOLINOMIMETIC DRUGS 19 PART III CHOLINORECEPTOR BLOCKING DRUGS 23 PART IV ADRENORECEPTOR ACTIVATING DRUGS 31 PART V ADRENORECEPTOR ANTAGONIST DRUGS 38 (3) AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYST...

Exam 2: NUR100/ NUR 100 (Latest 2024/ 2025 Update) Pharmacology | Review with Questions and Verified Answers| 100% Correct| Grade A – Fortis Q: what drug classes are CNS depressants? Answer: -benzodiazepines (-lam/-pam) -barbiturates (-barbital) centrally acting muscle relaxants (baclofen, cyclobenzaprine, etc) Q: which drug is used more, barbiturates or benzodiazepines? why? Answer: -benzodiazepines (-lam/-pam) -bc they have less harsh side effects, and they are more...

Ester Local Anesthetics CORRECT ANSWER Procaine, Tetracaine and Cocaine Amide Local Anesthetics CORRECT ANSWER Anything that is NOT Procaine, Tetracaine or Cocaine and ends in "-Caine" Lidocaine CORRECT ANSWER 1. SAFEST to use in children 2. 2% 3. pKa = 7.8 Bupivacaine CORRECT ANSWER 1. LEAST SAFE to use in children 2. 0.5% 3. pKa = 8.1 Mepivicaine CORRECT ANSWER 1. Causes LEAST amount of Vasodilation, thus can be packaged WITHOUT Epinephrine 2. 2% or 3% 3. pKa = 7.6 Arti...

Addison's disease A disease due to hyposecretion of glucocorticoids, characterized by low blood pressure, diarrhea, digestive disturbance, and a bronzelike pigmentation of the skin Adjunctive agents Agents that supplement the primary anesthetic agents to augment or enhance the effects of the primary agent 00:14 01:25 Allergenicity Having the property of an allergen, a substance that will elicit an allergic response in sensitive individuals Alveolus (plural: alv...

How does local anesthesia work? a. it initiates depolarization b. it blocks depolarization c. it allows sodium transport across the nerve membrane CORRECT ANSWER b. it blocks depolarization Which of the following makes local anesthetic most effective? a. rapid injection b. injecting a larger amount of anesthetic c. lipid solubility CORRECT ANSWER c. lipid solubility Local anesthetics typically produce vasoconstriction. True False CORRECT ANSWER False Amide-type local anest...

Lidocaine, Procaine, Cocaine, Benzocaine correct answers Tx: Local anesthetics MOA: blocks voltage sensitive Na channels (keeps them in open state), blocking action potential SE: decrease motor & autonomic activity, negative inotropic and chronotropic, smooth muscle relaxant M: plasma esterase (ester type), hepatic microsomal enzymes (amide type). Slow acetylators have prolonged action Benzodiazepines to treat OD Methemoglobinemia correct answers Hb oxidized by benzocaine (topical/pharyng...

NUR 101 INBDE Pharmacology Exam Review with 100% Correct Answers Ester Local Anesthetics *Ans* Procaine, Tetracaine and Cocaine Amide Local Anesthetics *Ans* Anything that is NOT Procaine, Tetracaine or Cocaine and ends in "-caine" Lidocaine *Ans* 1. SAFEST to use in children 2. 2% 3. pKa = 7.8 Bupivacaine *Ans* 1. LEAST SAFE to use in children 2. 0.5% 3. pKa = 8.1 Mepivicaine *Ans* 1. Causes LEAST amount of Vasodilation, thus can be packaged WITHOUT Epinephrine 2. 2% or 3% 3...

How do local anesthetics block the nerve impulse from reaching the brain? By permanently depolarizing the nerve cell membrane By overwhelming influx of fluoride ions By blocking sodium channels, thereby preventing nerve cell depolarization and impulse propagation By causing massive neurotransmitter release without uptake. By blocking sodium channels, thereby preventing nerve cell depolarization and impulse propagation How do local anesthetics stop working? By diffusion of the lo...

WREB Study Local Anesthesia & Questions and answers 2023/2024 verified to passHow does local anesthesia work? a. it initiates depolarization b. it blocks depolarization c. it allows sodium transport across the nerve membrane - correct answer b. it blocks depolarization Which of the following makes local anesthetic most effective? a. rapid injection b. injecting a larger amount of anesthetic c. lipid solubility - correct answer c. lipid solubility Local anesthetics typically produ...

WREB Study Local Anesthesia & NO Questions Clearly Answered 2024. How does local anesthesia work? a. it initiates depolarization b. it blocks depolarization c. it allows sodium transport across the nerve membrane - correct answer b. it blocks depolarization Which of the following makes local anesthetic most effective? a. rapid injection b. injecting a larger amount of anesthetic c. lipid solubility - correct answer c. lipid solubility Local anesthetics typically produce vasocons...