Pcb 3233 immunology Study guides, Class notes & Summaries

Single Positive - has either CD4 or CD8 CD2 and CD5 - perform adhesion and signaling. They are present during double negative stage Thymocytes rearrange which 3 genes at the same time? - Beta, gamma, and delta pTalpha - surrogate alpha chain. signals cell to halt gamma, delta, Beta chains, gene rearrangement and begin proliferation. What do macrophages do in the thymus? - continually remove dead cells What does TH1 cells do? - Activate macrophages Thymal Stromal Cells - Keeps BCR genes cl...

Which disease state is caused by loss of approximately 80% of the RAG proteins enzymatic activity and misssense mutation? (hint: infant has a red rash on the face and shoulders) - Omenn Syndrome Major histocompatibility complex class I presents: - Intracellular antigens to CD8 T cells __________ has an alpha chain and a beta chain in their structure while ________ only has an alpha chain in its structure? - MHC II, MHC I What process(es) are used after activation to make MHC I and II bindin...

PCB 3233 Immunology Exam 4 Practice Questions and Answers Positive Selection - Answer️️ -makes sure that your T-Cell recognizes one of your MHC. If it does not, then apoptosis Negative Selection - Answer️️ -Makes sure it does not recognize your peptide:MHC too strongly Does gamma: delta T-cells have to go through positive selection? - Answer️️ -No What does turning off RAG 1&2 do to your gene rearrangement? - Answer️️ -Preserve the current rearrangement Primary Lymphoi...

PCB 3233 IMMUNOLOGY - EXAM 3 QUESTIONS AND ANSWERS Which cell types can become a plasma cell? - Answer️️ -All the above (a memory B-cell, an activated B-cell, a centrocyte The types of human MHC II presenting molecules are: - Answer️️ - HLA-DP, HLA-DQ, HLA-DR which present peptide to CD4 T-cells __________ has an alpha chain and a beta chain in their structure while ________ only has an alpha chain in its structure? - Answer️️ -MHC II, MHC I What process(es) are used after a...

What process creates the variable region domain for both TCRs and BCRs? - Somatic Recombination What the different types IFN-1? - Alpha and Beta What are the differences and similarities between CD8 T Cells and NK cells? - The both have the same cytotoxic granules, NK cells are activated faster, because they come out of the bone marrow "ready to go". CD8 T cells recognizes MHC Class 1 + peptide (antigen) on a pathogen, while NK cells recognize normal MHC Class 1 molecules on the surface ...

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PCB 3233 Exam 4 Review Guide

PCB 3233 Exam 5 Study guide

PCB 3233 - Immunology Exam 3 Practice Questions and Answers (100% Pass) Helper T cells associate with which class of MHC molecules? - Answer️️ -MHC Class 2 (extracellular infection) Interferon function - Answer️️ -Viral fighting, they activate NK cells which then tell our infected cells to die by apoptosis. What process creates the variable region domain for both TCRs and BCRs? - Answer️️ -Somatic Recombination What the different types IFN-1? - Answer️️ -Alpha and Beta W...