Sbom - Study guides, Class notes & Summaries

acute testing - usually single dose study causes of confusion in the elderly - - sepsis - 'something in the head'- tumour, CVA, subdural, meningitis - medication - metabolic: dec Na, dec glucose, AKI chronic testing - Repeated doses for 1-2 yrs; used to investigate carcinogenicity clinical trials: phase 1 - Define route & metabolic fate in normal volunteers (n<50). Initial dose: usually 1/20th or 1/50th of effective dose in animals. ADR monitored by clinical biochemistry etc clinic...

if a patient needs IV fluids for routine maintenance alone, how much fluid do they need? - Answer 25-30 ml/kg/day how much electrolytes are needed per day? - Answer 1 mmol/kg/day (K+ Na+ Cl-) how much glucose is needed per day? - Answer 500-100g/day (to limit starvation ketosis) how is fluid lost everyday? - Answer - insensible losses e.g. sweat/breath (500ml/day)

16 y/o male with GSW to abdomen, perfed sleen... what percent of cardiac output normally goes to the brain - 14 % 19 y/o male with 2 gunshots on L thigh goes into hemorrhagic shock. which of the following changes would you expect to find - decreased venous capacity or capacitance A 25-year-old overweight African American man presents with concerns about his blood pressure. 3 months ago, he reports elevated blood pressure at a work health fair. He has checked his blood pressure in local gr...

A 23-year-old woman presents with fatigue and the recent onset of a yellowing of her skin. Her physical examination is remarkable for the presence of splenomegaly. Laboratory results are as follows: TESTRESULTSREFERENCE RANGEHematocrit3840-50 (male)36-44 (female)Hemoglobin12.6 g/dL13.8-17.2 g/dL (male)12.1-15.1 g/dL (female)RBC3.3 x 106/µl4.5-5.7 x 106/µl (male)3.9-5.0 x 106/µl (female)MCHC3731-36Platelets258,000/mm3130,000-400,000/mm3WBC5.4 x 103/mm34.0-11 x 103/mm3Neutrophils5740-75%Ly...

Based on clinical picture, what is the most likley diagnosis? - Answer Chronic myeloid leukemia A 32-year-old man presents with a 2-month history of weakness, weight loss, and a dragging sensation in the abdomen. On examination, there is pallor and splenomegaly. A complete blood picture reveals hemoglobin of 11.5gm%, red blood cell count of 4.1x106/mm3, leukocyte count of 120,000 cells/mm3, and platelet count of 550,000/mm3. Peripheral smear predominantly shows neutrophils, bands, and met...

40-year-old man develops a rash and malaise 2 weeks after taking ciprofloxacin to treat bronchitis. He has a normal physical examination. What finding makes the diagnosis of acute interstitial nephritis? - WBCs and white cell casts in urine specimen A 2-year-old boy with marked edema is seen by his pediatrician. Based on his prior medical history, his current history, and his current physical exam, a biopsy of his kidney is done. The pathologist discusses the case with the primary doctor. ...

Which of the following substances enzymatically causes the polymerization of plasma fibrinogen? Answer> Thrombin Which statement is correct: Damaged tissue releases a substance called tissue fibrinogen, which is mainly composed of phospholipids Damage to the vessel wall initiates what is called the intrinsic pathway The activation of protein coagulation factor plus the release of platelet thromboplastin eventually leads directly to the formation of thrombin The actual blood clotti...

which of the following changes would you expect to find - Answer decreased venous capacity or capacitance In which of the following lists of blood vessels is the sequence of vessels arranged from highest to lowest total cross-sectional area in the body? - Answer capillaries, arterioles, veins, arteries 16 y/o male with GSW to abdomen, perfed sleen... what percent of cardiac output normally goes to the brain - Answer 14 %

A 22-year-old man, who is a first year medical student, presents to your office with respiratory complaints. He is spending many hours working on the cadaver and has been breathing the fumes. After a careful history and physical examination, you conclude that he has asthma. Question What observation is most likely? - Hyper-responsiveness of the airways A 37-year-old male patient on your pulmonary therapy service has a history of asthma and is a chain smoker. By now, he has developed emphys...