NURS 5334 - M1 Questions With Complete Solutions

Prescriptive Authority - legal route to prescribe independently and without limitation Parts of a prescription - - prescriber name - license number - contact information - DEA number (prescriber and supervising) - patient name - DOB - allergies - name of medication - indication - strength - frequency - signature SIG - "let it be labeled"; instructions for the prescription Pharmacokinetics - the study of the drug movement throughout the body Ways for drugs to cross the cell membrane - 1. Channels 2. Pore transport systems - P-glycoprotein system 3. Direct penetration Absorption - the drug's movement from the site of administration into the blood Factors that affect absorption: - rate of dissolution, surface area, blood flow, lipid solubility, pH partitioning pH partitioning or ion trapping - drug molecules tend to accumulate on the side of the membrane where pH most favors ionization - i.e. Acidic drugs accumulate on the alkaline side, and basic drugs accumulate on the acidic side