Tentamen (uitwerkingen)

NURS 4010 Unit 1 Exam Antipsychotic/Neuroleptic Medications Questions With Verified Answers

0 keer verkocht

Vak
NURS4010

Instelling
NURS4010

[Meer zien]

Voorbeeld 2 van de 6 pagina's

Bekijk voorbeeld

Geupload op 8 mei 2024
Aantal pagina's 6
Geschreven in 2023/2024
Type Tentamen (uitwerkingen)
Bevat Vragen en antwoorden

nurs 4010 unit 1 exam antipsychoticneuroleptic me

Volgen

LectDan

Lid sinds 2 jaar 185 documenten verkocht

€10,40

In winkelwagen

Op verlanglijstje

100% tevredenheidsgarantie
Direct beschikbaar na je betaling
Lees online óf als PDF
Geen vaste maandelijkse kosten

NURS 4010 Unit 1 Exam
Antipsychotic/Neuroleptic Medications
Questions With Verified Answers
Bind with dopamine receptors (commonly D2 receptors - in all 4 pathways of the brain, causing side
effects)
MOA of Antipsychotic/Neuroleptic Medications

Antipsychotics
Used for schizophrenia, paranoia, psychosis, mania, severe anxiety, Tourette's, autism; Note: just b/c
someone is on an antipsychotic does not mean they have a thought disorder; Metabolized by the liver
and excreted in urine, feces, breastmilk; All cause weight gain r/t poor glycemic control

Mesolimbic, mesocortical, nigrostriatal, tuberoinfundibular
4 dopamine pathways of the brain

Positive s/sx (hallucinations, delusions), thought disorders, and aggressive and hostile symptoms
Excessive dopamine in the Mesolimbic Pathway contributes to what?

Negative symptoms and cognitive symptoms
The Mesocortical Pathway mediates what type of symptoms, which results from either a decrease in
dopamine or a "burnout" of neuronal systems; Could be due to glutamate overactivity; Antipsychotics
that block the dopamine in this pathway contribute to these symptoms (seen especially with first
generation antipsychotics); The newer antipsychotics do not cause this as much b/c they have a lower
affinity for the D2

Nigrostriatal Pathway
Part of the extrapyramidal nervous system and control motor movements

Rigidity, akinesia, bradykinesia, dystonia, tremors, etc.
Deficits in the Nigrostriatal Pathway can cause what s/sx?

Tics or other hyperkinetic movement disorders (ex. restless leg syndrome, Huntington's disease)
Increased dopamine in the Nigrostriatal Pathway can cause what s/sx?

Extra Pyramidal Symptoms (EPS)
When antipsychotics decrease dopamine in the Nigrostriatal Pathway, it causes what?

Tuberoinfundibular Pathway
Normally the neurons in this pathway are active and INHIBIT prolactin release; During postpartum
periods, their activity is decreased and prolactin increases so that lactation can occur; When
antipsychotics block dopamine in this pathway, it also causes in increase in prolactin (contributes to
the side effects of galactorrhea in women and gynecomastia in men)

Thioridazine (Mellaril), Acetophenazine (Tindal), Carphenazine (Proketazine), Pimozide (Orap), and
Loxapine

, 1st Generation or Typical Antipsychotics - that only come in a pill

Chlorpromazine (Thorazine), Trifluoperazine (Stelazine), Perphenazine (Trilafon), Mesoridazine
(Serentil), Trifluopromazine (Vesperin), Promazine (Sparine), Prochloperazine (Compazine),
Fluphaneazine (Prolixin), Thiothixene (Navane), Chlorprothixene (Taractan), Haloperidol (Haldol), and
Loxapine Succinate (Loxitane)
1st Generation or Typical Antipsychotics - that come in both a pill and injectable

Prolinix Deconoate (Fluphaneazine)
1st Generation or Typical Antipsychotic that comes in a long acting injectable; Get every 2 weeks,
which helps with compliance

Haldol Deconoate (Haloperidol)
1st Generation or Typical Antipsychotic that comes in a long acting injectable

Chlorpromazine (Thorazine)
1st medication in the 1st Generation or Typical Antipsychotics class to come out; FDA indicated for
intractable hiccups

Prochloperazine (Compazine)
1st Generation or Typical Antipsychotics that is FDA indicated for severe nausea and vomiting

Haldol (haloperidol)
Which 1st Generation or Typical Antipsychotic medication in IV form is not FDA approved?
- Is instead off label, meaning research approves it but is not FDA approved

pimozide (Orap)
1st Generation or Typical Antipsychotic that is FDA indicated for Tourettes who have failed standard
treatment

Prolong QT interval; Need EKG, and cannot mix with other drugs that could also prolong QT interval
What is a major s/sx that 1st Generation or Typical Antipsychotics can cause? What lab needs to be
taken during tx of these drugs?

1st Generation or Typical Antipsychotics
Great job in D2 receptors (strong affinity); Drives dopamine down; can cause negative s/sx or make
negative s/sx worse; Pregnancy category C (aren't prescribed if pregnant)

2nd Generation or Atypical Antipsychotics
Target D2 and 5-HT Receptors; Work differently - don't target D2 as much but also now hits serotonin
levels as well; Helps balance out serotonin imbalances; Can help with negative s/sx or not cause them;
Pregnancy category B (not as bad)

Clozapine (Clozaril, FazaClo), Olanzepine (Zyprexa Zydis), Quentiapine (Seroquel, Seroquel XR),
Risperidone (Risperdal), Aripiprazole (Abilify Discmelt), Paliperidone (Invega), Iloperidone (Fanapt),

Dit zijn jouw voordelen als je samenvattingen koopt bij Stuvia:

Bewezen kwaliteit door reviews

Studenten hebben al meer dan 850.000 samenvattingen beoordeeld. Zo weet jij zeker dat je de beste keuze maakt!

In een paar klikken geregeld

Geen gedoe — betaal gewoon eenmalig met iDeal, Bancontact of creditcard en je bent klaar. Geen abonnement nodig.

Focus op de essentie

Studenten maken samenvattingen voor studenten. Dat betekent: actuele inhoud waar jij écht wat aan hebt. Geen overbodige details!

Veelgestelde vragen

Wat krijg ik als ik dit document koop?

Je krijgt een PDF, die direct beschikbaar is na je aankoop. Het gekochte document is altijd, overal en oneindig toegankelijk via je profiel.

Tevredenheidsgarantie: hoe werkt dat?

Onze tevredenheidsgarantie zorgt ervoor dat je altijd een studiedocument vindt dat goed bij je past. Je vult een formulier in en onze klantenservice regelt de rest.

Van wie koop ik deze samenvatting?

Stuvia is een marktplaats, je koop dit document dus niet van ons, maar van verkoper LectDan. Stuvia faciliteert de betaling aan de verkoper.

Zit ik meteen vast aan een abonnement?

Nee, je koopt alleen deze samenvatting voor €10,40. Je zit daarna nergens aan vast.

Is Stuvia te vertrouwen?

4,6 sterren op Google & Trustpilot (+1000 reviews)

Afgelopen 30 dagen zijn er 69052 samenvattingen verkocht

Opgericht in 2010, al 15 jaar dé plek om samenvattingen te kopen

Start met verkopen

Tentamen (uitwerkingen)

NURS 4010 Unit 1 Exam Antipsychotic/Neuroleptic Medications Questions With Verified Answers

Document informatie

Onderwerpen

Geschreven voor

Verkoper

Ontvangen beoordelingen

Voorbeeld van de inhoud