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FGCU Pharmacology Exam 1 (Graded A+ actual test)
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Generic Drugs - Chemicals that are produced by companies involved solely in the manufacturing of drugs Bioavailability of the drug may be different than brand name drug Less expensive than brand name drug DEA Schedule III (3 examples) - Less abuse potential than schedule II and moderate depende...

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Voorbeeld van de inhoud

FGCU Pharmacology Exam 1
Generic Drugs - Chemicals that are produced by companies involved solely in the manufacturing
of drugs

Bioavailability of the drug may be different than brand name drug

Less expensive than brand name drug



DEA Schedule III (3 examples) - Less abuse potential than schedule II and moderate dependence
liability

Nonbarbiturate sedatives, nonamphetamine stimulates, limited amounts of certain narcotics

Drug Evaluation: Preclinical Trials - Drugs are tested on laboratory ANIMALS to see if the drug has
effects on living tissue organisms and to assess for adverse effects



Drug Evaluation: Phase I Studies - Chemicals tested on HEALTHY HUMANS volunteers

Informed consent is obtained

Usually male 150lbs

Women of childbearing age are eliminated

Drug may cause unknown harm to ova



Drug Evaluation: Phase II Studies - Drug trailed on informed PATIENTS WITH THE DISEASE that the
drug is intended to treat



Drug Evaluation: Phase III Studies - Drug used in VAST CLINICAL MARKET



Drug Evaluation: FDA Approval - Drugs that finish phase III trials are evaluated by the FDA; if
approved my be marketed



Drug Evaluation: Phase IV Studies - Continual evaluation of drug



The DEA has how many schedules of controlled substances? - 5

,DEA Schedule I (3 examples) - High abuse potential and NO accepted medical use

Heroin, marijuana, LSD



DEA Schedule II (3 examples) - High abuse potential with severe dependence liability

Narcotics, amphetamines, barbiturates



Medication Administration: Nursing Responsibility - Administering the drug

Assessing drug effects

Intervening to make the drug regimen more tolerable

Providing patient education about drugs and the drug regimen Monitoring the overall patient care plan
to prevent medication errors




DEA Schedule IV (3 examples) - Less abuse than schedule III and limited dependence liability

Some sedatives, anti-anxiety agents, nonarcotic analgesics



DEA Schedule V (3 examples) - Limited abuse potential

Small amounts of narcotics (codeine), antitussives, antidiarrheals

Limited quantities may be purchased directly from a pharmacist

Must be 18 w/ suitable identification

All transactions must be recorded



Why would DAW be written on a prescription? Who writes it? - So that generic drugs will not be
substituted for brand name drugs

It is written by the prescriber.



What are some problems with over-the-counter (OTC) drugs? - Mask the signs and symptoms of
underlying disease, making difficult diagnosis

, Could result in drug interactions and interfere with drug therapy

Can result in serious overdoes if not taken correctly



What is an example of a serious overdoses caused by an OTC? - Acetaminophen (Tylenol)
overdoes can result in liver failure and the need for a liver transplant



What is pharmacodynamics? - How the drug affects the body (the mechanism of action)

The study of the interactions between the chemical components of living systems and foreign in
chemicals, including drugs that enter living organisms



What is pharmacokinetics? - The way the body deals with the drug

The study of absorption, distribution, metabolism (biotransformation), and excretion of drugs



What is the onset of the drug, and is it part of the pharmacodynamics or pharmacokinetics? -
(Pharmacokinetics) how long it will take to see the beginning of the drugs therapeutic effect



What is a drug half life, and is it part of the pharmacodynamics or pharmacokinetics? What is the half life
affected by? - (Pharmacokinetics) The drug half life is how long it take the drug to decrease by
half.

Example 100mg acetaminophen given at 1500 half life is p4h

At 1900 the drug will be down to 50mg

At 2300 the drug will be down to 25mg

It is affected by absorption, distribution, metabolism, and excretion.



What is the peak effect, and is it part of the pharmacodynamics or pharmacokinetics? -
(Pharmacokinetics) how long it will take to see the maximum effect of the drug



What is the duration, and is it part of the pharmacodynamics or pharmacokinetics? -
(Pharmacokinetics) how long the patient will experience the drug effects

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