CGMBS DNA Polymorphisms and Human Identification Homework Questions And Answers Latest Updates
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CGMBS DNA Polymorphisms And Human Identificatio
DNA was isolated from a patient and cut with HaeIII. The resulting fragments were
separated by gel electrophoresis and transferred to a membrane. The fragments were
allowed to hybridize to a probe, and the resulting band pattern was compared with that
seen in another sample of DNA. Which of the ...
CGMBS DNA Polymorphisms and
Human Identification Homework
DNA was isolated from a patient and cut with HaeIII. The resulting fragments were
separated by gel electrophoresis and transferred to a membrane. The fragments were
allowed to hybridize to a probe, and the resulting band pattern was compared with that
seen in another sample of DNA. Which of the following methods is described?
a. RFLP by southern blot
b. VNTR by PCR
c. SNP by sequencing
d. STR by PCR - ✔️✔️RFLP by southern blot
Which of the following is used as a marker of gender?
a. D8S1179
b. Amelogenin
c. TPOX
d. Penta D - ✔️✔️Amelogenin
What is an expression for how many times more likely the child's allele is inherited from
the alleged father than by random occurrence of the allele in the general population? -
✔️✔️Paternity index
Which of the following STRs is a Y-STR
a. D5S818
b. vWA
c. Penta E
d. DYS385 - ✔️✔️DYS385
If a locus on chromosome 16 is homozygous, then the locus has - ✔️✔️The same
alleles on each chromosome 16 homolog
What is a microvariant? - ✔️✔️An STR allele missing base pairs in the repeat unit
Two peaks from different sources falling within a bin describe what relationship -
✔️✔️Identical alleles
The uniqueness of mitochondrial and Y-STR alleles is expressed by what measure? -
✔️✔️Discriminatory capacity
When two sources of DNA are compared by STR analysis in a crime scene, how many
differences between alleles will determine that the two sources are different? - ✔️✔️1
, Which are more likely to be successfully analyzed on highly degraded DNA?
a. Mini-STR
b. STR
c. RFLP
d. VNTR - ✔️✔️Mini-STR
How are mitochondrial polymorphisms inherited? - ✔️✔️Maternally
How many loci are considered core loci by the Federal Bureau of Investigation in the
Combined DNA Indexing System? - ✔️✔️13
How do STR and VNTR differ? - ✔️✔️STR have shorter repeat units than VNTR
A woman has been sexually assaulted by an unknown man. Which of the following
laboratory procedures can be used to more accurately analyze residual DNA left by the
man in an effort to identify him? - ✔️✔️Y-STR
Which of the following polymorphisms are tandem repeats of 1-8 bp?
a. Single nucleotide polymorphisms
b. Variable number tandem repeats
c. Short tandem repeats
d. Restriction fragment length polymorphisms - ✔️✔️Short tandem repeats
Which of the following polymorphisms can be used to compare DNA samples derived
from males but not females?
a. STR
b. Y-STR
c. RFLP
d. VNTR - ✔️✔️Y-STR
Southern blot is used to detect which of the following polymorphisms?
a. Edited RNA
b. Alternative splicing
c. Restriction fragment length polymorphisms
d. Modified nucleotides - ✔️✔️Restriction fragment length polymorphisms
THO1, D8S1179, and D2S11 are examples of which of the following?
a. RFLP
b. SINE
c. STR
d. SNP - ✔️✔️STR
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