NURP 424 Pharm Exam 1 Questions And Answers With Verified Study Solutions
1 keer bekeken 0 keer verkocht
Vak
NURP 424
Instelling
NURP 424
NURP 424 Pharm Exam 1 Questions And Answers With Verified Study Solutions
Considerations when prescribing: ANS I: Indication
C: contraindication
P: precautions or interactions
C: cost/compliance
E: efficacy
A: adverse effects
D: dose/duration/directions
Drug approval process: Phase I ANS...
nurp 424 pharm exam 1 questions and answers with v
nurp 424 pharm exam 1 questions and answers
considerations when prescribing ans i indicati
Geschreven voor
NURP 424
NURP 424
Verkoper
Volgen
Nipsey
Ontvangen beoordelingen
Voorbeeld van de inhoud
NURP 424 Pharm Exam 1 Questions And Answers
With Verified Study Solutions
Considerations when prescribing: ANS I: Indication
C: contraindication
P: precautions or interactions
C: cost/compliance
E: efficacy
A: adverse effects
D: dose/duration/directions
Drug approval process: Phase I ANS Phase I: safety and safe dosage- how the drug is tolerated at
different doses- does not determine efficacy; studies the pharmacokinetics of the drug
(After the preclinical animal testing phase)
Drug Approval Process: Phase II ANS Phase II: determine dosage and efficacy; determine short-
term risks
Drug Approval Process: Phase III ANS Phase III: controlled and uncontrolled clinical trials of
safety and efficacy in multiple settings; submit a new drug application (NDA) to the FDA
-Is it better than current treatment?
Drug Approval Process: Post Market ANS Phase IV or Post market research: has no fixed
duration, further report adverse events
DEA Controlled Drug Schedules: Schedule 1 ANS - No accepted medical use
-No legal use permitted
- For registered research facilities only
Heroin, LSD, mescaline, peyote, marijuana*(state to state)
,DEA Controlled Drug Schedules: Schedule 2 ANS -No refills permitted (only 30 day supply)
-No phone orders unless you have a written one within 7 days
-E-prescribe is OK
- expires in 72hrs id not filled
Narcotics, stimulants, depressants (phenobarbital, secobarbital)
DEA Controlled Drug Schedules: Schedule 3 ANS -must be rewritten after 6 months or five
refills
-phone and fax OK
Some narcotics (Percocet, hydrocodone) Some stimulants (benzphetamine, chlorpheniramine,
diethylpropion)
Anabolic steroids, testosterone
DEA Controlled Drug Schedules: Schedule 4 ANS -same as schedule 3, penalties for illegal
possessions are different
-low potential for abuse per DEA
pentazocine, phentermine, benzos, meprobamate
DEA Controlled Drug Schedules: Schedule 5 ANS - same as all prescription drugs
-may be dispensed without prescription unless regulated by the state
loperamide, cough meds, pregabalin
Adverse Drug Reactions: Pharmacological ANS - majority of adverse reactions
-predictable
-dose-related
-85-90% of ADRs
(Hypotension from antihypertensives)
Adverse Drug Reactions: Idiosyncratic ANS -unpredictable
, -Not dose-related
(Stevens-Johnson syndrome from lamictal or ibuprofen)
Immune-Mediated ADR: Type 1 ANS -igE mediated, immediate type
-previously sensitize person
-hypersensitivity like atopic dermatitis, hives, angioedema or anaphylaxis
Immune-Mediated ADR: Type 2 ANS - antibody-dependent cytotoxicity
- "autoimmune response"
- improvement with removal of drug
- HIT or hemolytic anemia, neutropenia
Immune-Mediated ADR: Type 3 ANS -immune complex hypersensitivity (Arthus reaction to
tetanus vaccine)
- "serum sickness"
-Aggregates of antigens and IgG create insoluble immune complexes in blood vessels which can take
a week to occur and cause vasculitis
- arthralgia, fever, swollen lymph nodes, and splenomegaly
-involvement of tissue
Immune-Mediated ADR: Type 4 ANS -cell-mediated or delayed hypersensitivity
- Usually occurs more than 12 hours after exposure to the allergen, with a maximal reaction time
between 48 and 72 hrs
-Ex. drug rash, eosinophilia, and systemic syndrome (DRESS), Stevens Johnsons, contact dermatitis
Time-Related ADR ANS -Rapid: during or immediately following admin
-First-dose: occur immediately after the first dose
-Immediate: within one hour of exposure
-Delayed: one hour after exposure
Voordelen van het kopen van samenvattingen bij Stuvia op een rij:
√ Verzekerd van kwaliteit door reviews
Stuvia-klanten hebben meer dan 700.000 samenvattingen beoordeeld. Zo weet je zeker dat je de beste documenten koopt!
Snel en makkelijk kopen
Je betaalt supersnel en eenmalig met iDeal, Bancontact of creditcard voor de samenvatting. Zonder lidmaatschap.
Focus op de essentie
Samenvattingen worden geschreven voor en door anderen. Daarom zijn de samenvattingen altijd betrouwbaar en actueel. Zo kom je snel tot de kern!
Veelgestelde vragen
Wat krijg ik als ik dit document koop?
Je krijgt een PDF, die direct beschikbaar is na je aankoop. Het gekochte document is altijd, overal en oneindig toegankelijk via je profiel.
Tevredenheidsgarantie: hoe werkt dat?
Onze tevredenheidsgarantie zorgt ervoor dat je altijd een studiedocument vindt dat goed bij je past. Je vult een formulier in en onze klantenservice regelt de rest.
Van wie koop ik deze samenvatting?
Stuvia is een marktplaats, je koop dit document dus niet van ons, maar van verkoper Nipsey. Stuvia faciliteert de betaling aan de verkoper.
Zit ik meteen vast aan een abonnement?
Nee, je koopt alleen deze samenvatting voor €12,60. Je zit daarna nergens aan vast.
