100% tevredenheidsgarantie Direct beschikbaar na betaling Zowel online als in PDF Je zit nergens aan vast
logo-home
MDSC 321 Midterm 1 Exam Questions and Answers 100% Solved €13,23   In winkelwagen

Tentamen (uitwerkingen)

MDSC 321 Midterm 1 Exam Questions and Answers 100% Solved

 6 keer bekeken  0 keer verkocht
  • Vak
  • MDSC
  • Instelling
  • MDSC

MDSC 321 Midterm 1 Exam Questions and Answers 100% Solved What makes a good vaccine? - Variolation or Inoculation (Safety) Vaccination (Cost) Effectiveness Type of Immunity Vaccine Production - Dried up small pox scabs, ship live cows to make the vaccine, own farms for vaccine production, in...

[Meer zien]

Voorbeeld 4 van de 39  pagina's

  • 1 november 2024
  • 39
  • 2024/2025
  • Tentamen (uitwerkingen)
  • Vragen en antwoorden
  • MDSC
  • MDSC
avatar-seller
©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
MDSC 321 Midterm 1 Exam Questions

and Answers 100% Solved


What makes a good vaccine? - ✔✔Variolation or Inoculation (Safety)

Vaccination (Cost)

Effectiveness

Type of Immunity

Vaccine Production - ✔✔Dried up small pox scabs, ship live cows to make

the vaccine, own farms for vaccine production, infect egg with virus to

make the vaccine, DNA vaccines take a gene that codes for one of the

proteins to inject with the piece of DNA. Can't control where gene goes.

Vaccine Composition (Live Attenuated) - ✔✔Weakened or less virulent

pathogen

Actually infect the host

Robust immune response

Long lasting memory

Ex. Measles, Mumps

,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Vaccine Composition (Killed) - ✔✔Whole killed pathogens (lots of potential

antigens)

Unable to infect the host

Weaker, short lived immunity

Often requires multiple boosters

Ex. Polio, Influenza

Vaccine Composition (Subunit or Toxoid) - ✔✔Specific molecules isolated

from a pathogen

Unable to infect the host

Weaker, short lived humoral (Ab) immunity

Often requires multiple boosters

Ex. Diphtheria, Tetanus

How is vaccination influenced by public perception? - ✔✔Autism, falsified

data, fraudulent. Not immunized you will get the disease. Herd immunity

threshold for a number of infectious diseases such as measles, diphtheria,

mumps etc.

Do we need to be vaccinated against everything? - ✔✔Effect of vaccinating

for one disease on other disease.

- Chicken pox and shingles are cause by the same virus

,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Chicken pox significant decrease but increase in shingles people are not as

exposed to chicken pox and your immune system gets lazy

How has our world changed? - ✔✔Smallpox is the only disease eradicated

in history of humans by world wide vaccination effort. Spend $1 on a

vaccine and save $30

Are antibodies a silver bullet drug? - ✔✔Stick to a target and mutualize

each other so then the disease cannot stick to your cells and infect you.

Antibodies - Therapeutics - ✔✔-Antibodies are a protein produced by the

immune system that specifically recognizes target molecules

-Antibody therapeutics bind and neutralize targets, activate cells, kill cells,

and modulate immunity

-Represents the first immune treatments (>100 years ago)

- More than 30 licenced monoclonal Ab are sold in the US for treatment of

human disease

-8 /20 best selling biotech drugs were antibodies

-Currently used to treat cancers (colon, brain, lymphoma, leukemia, breast)

- Treat autoimmunity (lupus, arthritis, MS, asthma, IBD, Crohn's, diabetes)

- Treat infections (Hep B, HIV, sepsis, rabies, tetanus, C.difficile, anthrax)

- Prevent transplant rejection

, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Antibodies AB structures developed from non-rodent/non-primate species -

✔✔Not all anitbodies are the same, structural differences confer functional

differences

IgM- sticks to target

IgD-

IgG-making when you vaccinate someone

IgE-allergies

IgA- GI tract keeps gut lining from getting effected

Antibodies - Structure - ✔✔Bispecific - could recognize two things are the

same time

"Smart Drugs"- Immunotoxins/ Antibody Drug Conjugates (ADC) -

✔✔Direct a drug to a specific target recognized by the antibody.

Conventional Chemotherapy: recognize the tumor cell, place the drug and

kill it

Infectious Disease - ✔✔Worldwide, 1 in 3 deaths is attributable to

infectious disease

Vast majority of these deaths are preventable by vaccine

Making progress but one of the biggest threats is emerging and re-

emerging disease

Voordelen van het kopen van samenvattingen bij Stuvia op een rij:

√  	Verzekerd van kwaliteit door reviews

√ Verzekerd van kwaliteit door reviews

Stuvia-klanten hebben meer dan 700.000 samenvattingen beoordeeld. Zo weet je zeker dat je de beste documenten koopt!

Snel en makkelijk kopen

Snel en makkelijk kopen

Je betaalt supersnel en eenmalig met iDeal, Bancontact of creditcard voor de samenvatting. Zonder lidmaatschap.

Focus op de essentie

Focus op de essentie

Samenvattingen worden geschreven voor en door anderen. Daarom zijn de samenvattingen altijd betrouwbaar en actueel. Zo kom je snel tot de kern!

Veelgestelde vragen

Wat krijg ik als ik dit document koop?

Je krijgt een PDF, die direct beschikbaar is na je aankoop. Het gekochte document is altijd, overal en oneindig toegankelijk via je profiel.

Tevredenheidsgarantie: hoe werkt dat?

Onze tevredenheidsgarantie zorgt ervoor dat je altijd een studiedocument vindt dat goed bij je past. Je vult een formulier in en onze klantenservice regelt de rest.

Van wie koop ik deze samenvatting?

Stuvia is een marktplaats, je koop dit document dus niet van ons, maar van verkoper NinjaNerd. Stuvia faciliteert de betaling aan de verkoper.

Zit ik meteen vast aan een abonnement?

Nee, je koopt alleen deze samenvatting voor €13,23. Je zit daarna nergens aan vast.

Is Stuvia te vertrouwen?

4,6 sterren op Google & Trustpilot (+1000 reviews)

Afgelopen 30 dagen zijn er 67096 samenvattingen verkocht

Opgericht in 2010, al 14 jaar dé plek om samenvattingen te kopen

Start met verkopen
€13,23
  • (0)
  Kopen