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Test Bank - Cellular and Molecular Immunology, 10th Edition (Abbas, 2022), Chapter 1-21 | All Chapters €16,30   In winkelwagen
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Test Bank - Cellular and Molecular Immunology, 10th Edition (Abbas, 2022), Chapter 1-21 | All Chapters
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  • 9780323757485 edition
  • 10th edition
  • cellular and molecular
  • test bank cellular and molecular immunology 10t
  • test bank
  • cellular and molecular immunology
  • test bank cellular and molecular immunolog

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  • Test Bank - Cellular and Molecular Immunology, 10th Edition (Abbas, 2022), Chapter 1-21 | All Chapters
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  • Samenvatting Moleculaire en cellulaire immunologie (1019FBDBIC)
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Voorbeeld van de inhoud

,DOWNLOADTHETestBankforCellularandMolecularImmunology10th
EditionAbbas


Abbas,Lichtman,andPillai:CellularandMolecularImmunology,10thEdition v




TestBank

Chapter2:CellsandTissuesoftheImmuneSystemMatching
V V V




Questions1-5
V




Match eachofthedescriptions in questions1-5with theappropriatename(A-M)ofananatomicfeature of
v V V V V V V V V V




lymphoidtissues.
V V




A. Periarteriolarlymphoidsheath V V




B. Thymicmedulla
C. Thymiccortex
D. Parafollicularcortexoflymphnode V V V V




E. Hematopoieticbonemarrow V V




F. Afferentlymphatic
G. Efferent lymphatic v



H. Marginalzone
I. Redpulpofspleen
J. Whitepulpofspleen
K. Epidermis
L. Dermis
M. Peyer’spatch

1. LocationofmostTlymphocytesin thespleen
V V v




ANS:A.Theperiarteriolarlymphoidsheathsurroundsthecentralarteriesinthespleenand istheT cell zone V V V




inthisorgan.
V V V




2. Vesselsthatdrain lymphawayfromalymphnode v v V




ANS:G.Efferentlymphaticvesselsdrainlymphawayfromlymphnodes;afferentvesselsdrain
V V V V V V V V V V V V




lymphintolymphnodes.
V V V V




3. SiteofleastmatureTcellprecursorsinthethymus
V V V




ANS: C.Bonemarrow–derivedTcell precursors first enterthe thymiccortex and migrate
V V V V V V V V V V V V




intothemedullaastheybecomemoremature.
V V V V V V V




4. LocationofLangerhanscells V V




ANS:K.Langerhanscellsaredendriticcellsintheepidermisoftheskinthatdevelopfromfetalmacrophages.
V V V V V V V V V V V V V V V V




Copyright © 2022 Elsevier Inc. All rights reserved.
V n n n n n V



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,DOWNLOADTHETestBankforCellularandMolecularImmunology10th
EditionAbbas



5. Lymphoid aggregateof themucosal immunesystem V v V




ANS: M. Peyer’s patches are B cell–rich lymphoid aggregates located in the submucosa of the
V V V V V V V V V V V V V V




smallintestine.
V




MultipleChoice V




6. Which ofthefollowingisthegenerative(primary)lymphoidorgan forTlymphocytes?
v V V V V V V V




A. Bonemarrow
B. Spleen
C. Lymphnode
D. Thymus
E. Tonsil


ANS: D. Generative (primary) lymphoid organs are the organs where lymphocytes first express
V V V V V V V V V V V V




antigen receptors and attain functional maturity. Although T cell precursors arise in the bone marrow,
V V V V V V V V V V V V V V V




these precursors migrate to the thymus, where maturation takes place. In contrast, B cells mature in the
V V V V V V V V V V V V V V V V V




bone marrow. Spleen, lymph node, and tonsil are secondary lymphoid organs populated by mature B
V V V V V V V V V V V V V V V




andTcells.
V V




7. Whichofthefollowingstatementsabouttissue-residentmacrophagesiscorrect?
V V V V V V V V V




A. Theyareallderivedfrombloodmonocytesthatentertissuesduringinfections V V V V V V




B. Manyofthesecellsfirstpopulatetissuesduringfetaldevelopment V V V V V V




C. Theydifferentiatefrom different kindsofepithelial cellsineachtissue V v V V V V V




D. Theyconstantlyrecirculatebetweendifferenttissues V V V V V




E. Theyareprofessionalantigen-presenting cellsthat activate naive Tcellsthat migrateinto V v v



tissues
V




ANS: B. Many tissue-resident macrophages are derived from fetal yolk sac and fetal liver precursors
V V V V V V V V V V V V V V




and establish residence in the different tissues during fetal development. Other tissue- resident
V V V V V V V V V V V V V




macrophages are derived from bone marrow–derived blood monocytes that enter tissues under
V V V V V V V V V V V V




normal conditions or during infections. Epithelial cells do not differentiate into macrophages. Once in
V V V V V V V V V V V V V V




the tissue, tissue-resident macrophages cells do not leave to recirculate. Naive T cells do not usually
V V V V V V V V V V V V V V V V




enter non-lymphoid tissues, and tissue-resident macrophages have no role in presenting antigen to
V V V V V V V V V V V V V




naiveTcells.
V V V




8. Which typeofleukocyteisthe mostabundantintheblood of a healthyadult? V V V V V V v V




A. Monocytes
B. Blymphocytes
C. Tlymphocytes
D. Polymorphonuclearleukocytes V




E. Basophils




Copyright © 2022 Elsevier Inc. All rights reserved. V n n n n n V



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, DOWNLOADTHETestBankforCellularandMolecularImmunology10th
EditionAbbas


ANS: D. Polymorphonuclear leukocytes (or neutrophils) are the most abundant blood leukocyte (~
V V V V V V V V V V V V




4,000/mm3),abouttwicethenumberofBandTlymphocytescombined.
V V V V V V V V V V v V




9. Whichofthefollowingisafeatureoffibroblasticreticularcells(FRCs)?
V V V V V V V V




A. Theylinethelumensoflymphaticsenteringlymphnodes V V V




B. Theyarederivedfromhematopoieticprecursors V V V




C. TheyplayacriticalroleinestablishingwherelymphocytesarelocatedinlymphnodesV V V V V V V V V V




D. TheysecretecytokinesthatstimulateTcellproliferation V V V




E. Theyarephagocyticcellsofinnateimmunitythatkillmicrobes V V V V




ANS: C. FRCs are mesenchymal-derived (not haematopoietically-derived) cells with properties of
V V V V V V V V V V




muscle and fibroblast (myofibroblasts) that drive formation of secondary lymphoid organs during
V V V V V V V V V V V V




embryonic development and contribute to the anatomic segregation and movement of lymphocytes and
V V V V V V V V V V V V V




dendritic cells in secondary lymphoid organs. They are not phagocytic, have no direct antimicrobial
V V V V V V V V V V V V V V




effectorfunctions, donotsecrete IL-2orotherTcell growth factors, and donot linelumensoflymphatics.
V V V V V V V V V V V V V V V V V V V




10. Which type of cell is most important in capturing protein antigens of microbes
V V V V V V V V V V V V




thatenterthroughepithelialbarriersandpresentingthemtonaiveTcellsinsecondarylymphoid
V V V V V V V V V V V V




organs?
V




A. Classicaldendriticcells V V




B. Plasmacytoid dendriticcells V V




C. Plasmacells
D. Macrophages
E. Folliculardendriticcells V




ANS: A. Classical (or conventional) dendritic cells (DCs) are the main cell type that brings microbial
V V V V V V V V V V V V V V V




antigens from infected tissues into draining lymph nodes and presents peptides derived from these
V V V V V V V V V V V V V V




antigens to naive T cells that circulate though the lymph nodes. Plasmacytoid DCs secrete type 1
V V V V V V V V V V V V V V V V




interferons in response to viral infection. Plasma cells are antibody-secreting cells derived from B cells
V V V V V V V V V V V V V V V




and do not present antigen to T cells. Macrophages can present antigen to effector T cells, but they are
V V V V V V V V V V V V V V V V V V V




not efficient activators of naive T cells. Follicular dendritic cells displayantigenstoBcellsonlymphoid
V V V V V V V V V V V V V V V V V




follicles.
V




Copyright © 2022 Elsevier Inc. All rights reserved. V n n n n n V



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