Chlorambucil - Study guides, Class notes & Summaries

Pharmacology Evolve HESI WITH Questions and correct answers latest update Neostigmine bromide and atropine sulfate, both anticholinergic drugs, reverse the respiratory muscle paralysis caused by pancuronium bromide. Options A, C, and D are not antagonists to pancuronium bromide and would not be helpful in reversing the effects of the drug compared with the use of anticholinergics. A client with viral influenza is receiving vitamin C, 1000 mg PO daily, and acetaminophen elixir, 650 mg P...

PHARMACOLOGY EVOLVE HESI EXAM WITH QUESTIONS AND WELL VERIFIED ANSWERS[GRADED A+] ACTUAL EXAM 100% A 19-year-old male client who has sustained a severe head injury is intubated and placed on assisted mechanical ventilation. To facilitate optimal ventilation and prevent the client from "fighting" the ventilator, the health care provider administers pancuronium bromide IV, with adjunctive opioid analgesia. What medication should be immediately accessible for a potential complicati...

Alkylating Agents correct answer: Chlorambucil (PO) -Kills in ALL phases of cell cycle -Reacts with DNA/RNA -Best for slow growing cancers Mostly IV Given in cycles Amifostine + Cisplatin Mesna + Ifosfomide Allopurinol Antimetabolites correct answer: Methotrexate (IV, PO) -Inhibit DNA synthesis by blocking thymidylate, DNA polymerase, or folic acid reductase -In S phase of cell cycle -Used in rapidly dividing cancers Methotrexate crosses BBB Leucovorin is given to...

Rituximab mechanism of action - correct answer Anti-CD20 monoclonal antibody Mutations that lead to favorable outcomes in CLL - correct answer Mutated IGHV and 13q- Indications for treatment in CLL (5) - correct answer -Advanced stage -Symptomatic at presentation (fatigued, weight loss, night sweats, fever) -End organ dysfunction -Enlarged spleen o...

Alkylating agents Classification Break DNA helix strand, thereby interfering with DNA replication Altretamine (Hexalen) Alkylating Agent PO Ovarian CA Side effects- nausea, vomiting, skin rash, hypersensitivity reaction, diarrhea Dose limiting - neuro-toxicity, peripheral neuropathy, myelosuppression Bendamustine (Treanda/Bendeka) Alkylating agent IV CLL or Indolent NHL Side effects- pyrexia, nausea, vomiting, skin reactions, TLS, hepatotoxicity, vein irritation Dose li...

Pharmacology Final Ivy Tech Exam Questions With Correct Answers Chloroquine - answerClass: Antimalarial -oquine Action: Inhibits reproduction Use: Treats Malaria Adverse effects: -retinotherapy -hepatic dysfunction -incrased psoriasis exacerbation Interactions: -Combination quinine=risk for cardiac toxicity & convulstions Interventions/Education: -take 1-2 weeks prior to travel; 4-6 weeks after -regular eye exams -monitor liver enzymes: AST/ALT -take with meals metronidazole - a...

melanoma - Stage I or II - CORRECT ANS surgery melanoma - Stage III - CORRECT ANS nivolumab, ipilumumab melanoma - BRAF positive Stage III - CORRECT ANS dabrafenib + trametinib melanoma - BRAF positive Stage IV, aggressive, bulky, symptomatic - CORRECT ANS dabrafenib + trametinib, vemurafenib + cobimetinib melanoma - Unresectable stage III with in-transit lesions - CORRECT ANS Talimogene Laherparepvec (T-VEC) melanoma - Stage IV - CORRECT ANS nivolumab, pembrol...

Lesson 1: Foundations to Set the Stage - answer Focusing on Cellular Structure and Function - answer The Normal Cell Cycle - answer -The cell cycle refers to the ordered seres of processes of DNA replication and mitosis, or cell division -Cell nucleus regulates these processes by gathering and processing complexes molecular information Interphase and Mitotic Phase - answer Cell division produces two identical cells through these two major phases During interphase: - answer Cell ...

PHARMACOLOGY HESI PRACTICE STUDY GUIDE A 19-year-old male client who has sustained a severe head injury is intubated and placed on assisted mechanical ventilation. To facilitate optimal ventilation and prevent the client from "fighting" the ventilator, the health care provider administers pancuronium bromide IV, with adjunctive opioid analgesia. What medication should be immediately accessible for a potential complication with this drug? A. Dantrolene sodium B. Neostigmine bromide...

Alkylating agents - correct answer Classification Break DNA helix strand, thereby interfering with DNA replication Altretamine (Hexalen) - correct answer Alkylating Agent PO Ovarian CA Side effects- nausea, vomiting, skin rash, hypersensitivity reaction, diarrhea Dose limiting - neuro-toxicity, peripheral neuropathy, myelosuppression Bendamustine (Treanda/Bendeka) - correct answer Alkylating agent IV CLL or Indolent NHL Side effects- pyrexia, nausea, vomiting, skin reactions, TLS, ...