Fludarabine - Study guides, Class notes & Summaries

vesicants - ANSWERbleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin, melphalan, taxol, vincristine cisplatin antidote - ANSWERsodium thiosulfate doxorubicin antidote - ANSWERDexrazoxane vincristine antidote - ANSWERhyaluronidase Alkylating agents - ANSWERbusulfan, cytoxan, melphalan, ifosfamide, carmustine; cell cycle non-specific; affects heme, GI, reproductive antimetabolites - ANSWERmethotrexate, 5-FU, cytarabine, gemcitabine, fludarabine; cell cycle speci...

Predictors of PDL1/PD1 inhibitor response Presence of tumor CD8 cell infiltration High cancer genome burden High levels of cancer PD-L1 expression (PD1 is on the cytotoxic T cell) Ipilimumab CTLA4 inhibitor Nivolumab PD-1 inhibitor Regorafenib VEGF inhibitor Bevacizumab Monoclonal antibody against VEGF-A. Inhibits angiogenesis. Pembrolizumab PD-1 inhibitor Atezolizumab PD-L1 inhibitor Avelumab PD-L1 inhibitor Durvalumab PD-L1 inhibitor Cemiplimab PD-1 inhibitor fo...

BMTCN TEST C QUESTIONS AND ANSWERS 2024 GRADED A+ Myeloid progenitors give rise to which of the following types of cells during hematopoiesis? A. NK cells B. Plasma Cells C. Erythrocytes D. T lymphocytes Ans- D. T lymphocytes Myeloid progenitors give rise to erythrocytes Which of the following would be an optimal donor choice for a 26-year-old Caucasian male with acute myeloid leukemia? A. A 35-year-old mother of four B. A 30-year-old male with a body mass index of 25 C. The ...

BMTCN TEST B ACTUAL QUESTIONS AND ANSWERS 2024 GRADED A+ Transplant-related toxicity is a barrier that contributes to the under utilization for which of the following diseases? A. Non-Hodgkin lymphoma B. Acute myeloid leukemia C. Sickle cell disease D. Neuroblastoma Ans- C. Sickle cell disease Despite success of HSCT in sickle cell disease, barriers to successful HSCT include lack of a suitable donor, transplant related toxicity and immunologic graft rejection. Which of the foll...

Chemotherapy Certification Exam Questions and Answers 100% Pass Doxorubicin - Correct Answer ️️ -Cardiotoxic TISSUE VESICANT Baseline MUGA and total dose (CONCERN at 550 mg/m2) URINE=RED IF EXTRAVASATION OCCURS= cool/ice + Totect Idamycin - Correct Answer ️️ -Cardiotoxic (cardiomyopathy) Bleomycin - Correct Answer ️️ -AVOID oxygen supplementation Methotrexate - Correct Answer ️️ -*Leukovorin decreases cytotoxicity* Pemetrexed - Correct Answer ️️ -Vitamin B12 & folic...

BMTCN TEST BANK ACTUAL QUESTIONS AND ANSWERS WITH COMPLETE SOLUTION BMTCN TEST BANK ACTUAL QUESTIONS AND ANSWERS WITH COMPLETE SOLUTION The administration of Epstein-Barr virus (EBV) cytotoxic T-lymphocytes has been found to be a feasible therapeutic option in which EBV mediated-disease process? a) Lymphoproliferative disease b) Neuroblastoma c) Nasopharyngeal rhabdomyosarcoma d) Acute lymphocytic leukemia Ans- A Donor leukocyte infusion is an appropriate treatment option for a ...

Which of the following studies should be completed at regular intervals for a patient receiving long-term steroids? A. Positron emission tomography scan B. Magnetic resonance imaging C. Dual energy x-ray absorptiometry D. Computed tomography scan C. Dual energy x-ray absorptiometry The major histocompatibility complex is responsible for: A. identification of self versus non-self. B. the release of histamine during a hemolytic transfusion reaction. C. the release of hematopoiet...

BMTCN ATG - correct answer anti t-cell globulin prevents GVHD, graft failure premeds: Tylenol, corticosteroids, Benadryl SE: hypotension, chills, rigors, fevers, pulmonary edema serum sickness - correct answer ATG myalgias, arthralgias, fever, rash, hand/facial edema give steroids BCNU (carmustine) - correct answer alkylating agent pre/post hydration SE: n/v, nephrotoxicity (elevated creat), pulmonary toxicity (pulmonary fibrosis, acute lung injury) infusion rx: feeling drunk, hy...

BMTCN Free Test Questions and Answers (2023/2024) Rated A+ Which of the following studies should be completed at regular intervals for a patient receiving long-term steroids? A. Positron emission tomography scan B. Magnetic resonance imaging C. Dual energy x-ray absorptiometry D. Computed tomography scan C. Dual energy x-ray absorptiometry The major histocompatibility complex is responsible for: A. identification of self versus non-self. B. the release of histamine during a hemolytic tran...

Doxorubicin - Answer Cardiotoxic TISSUE VESICANT Baseline MUGA and total dose (CONCERN at 550 mg/m2) URINE=RED IF EXTRAVASATION OCCURS= cool/ice + Totect Idamycin - Answer Cardiotoxic (cardiomyopathy) Bleomycin - Answer AVOID oxygen supplementation Methotrexate - Answer *Leukovorin decreases cytotoxicity* Pemetrexed - Answer Vitamin B12 & folic acid supplements to decrease toxicity Fludarabine - Answer Immunosuppression Thioguanine - Answer Bone Marrow Suppres...