Induced mutation - Study guides, Class notes & Summaries

Cmmb403 midterm exam with 100% correct answers Holt-Oram - answer____ syndrome is a human disease w a developmental basis that causes forelimb and heart defects where radius is missing and theres a hole btw ventricles so oxygenated and deoxygenated blood mixes. It is caused by a mutation of ONE copy of the TBX5 gene that codes for a transcription factor TBX5 - answerthe transcription factor that is mutated in Holt-Oram syndrome - is expressed in the forelimb and the heart (NOT the hind li...

Mutations - Genetics 3333 Test Questions and Answers Spontaneous Mutations - Answer-- Mistakes during replication or recombination - Wrong nucleotide is inserted - Too many nucleotides are inserted or deleted Tautomeric Shift - Answer-Rearrangement of bonds in a base so that its H bonding potential changes Induced Mutations - Answer-A mutagen damages the DNA - Damage causes a base to change its H bonding - The mistake in base pairing is passed to progeny cells - Ex: UV light, Ionizi...

1. Which one among the following statements is FALSE about DNA? (A) Located in chromosomes (B) Carries genetic information from parent to offspring (C) Abundantly found in the cytosol (D) There is a precise correlation between amount of DNA and number of sets of chromosome per cell 2. Which one among the following acts as the inducer of lac operon? (A) Glucose (B) Fructose (C) Lactose (D) Galactose 3. Kary Mullis is associated with (A) RFLP (B) PCR (C) Phosphorylation reaction ...

Pyrimidine dimers formed in DNA due to UV radiation can be repaired by? SOS repair Double strand break repair Mismatch repair Photoreactivation repair (nucleotide excision repair) Base excision repair - CORRECT ANSWER Photoreactivation repair (nucleotide excision repair) Which of the following repair mechanisms uses methyl groups to distinguish between parental and daughter strands? Answers: Mismatch repair Photoreactivation repair (Nucleotide excision repair) SOS repair Doubl...

spontaneous mutations mutations that arise without external influence - naturally occurring induced mutations mutations that are derived by exposure to mutagenic agents or procedures - occur at a much higher frequency than spontaneous somatic mutations mutations that occur in somatic cells - will not be passed on to next generation mosaic individual containing two or more types of cells that differ in their genetic composition - e.g. cancer chimera a single individual composed of two (or mor...

activators - TFs that increase the levels of transcription initiation Adaptive mutations - evolutionary change and adaptation to new environments, stressful conditions darwins birbs AP - activator proteins ARE - AP2 response elements Base analogs (chem induced - 5-bromouracil resembles thymine, except that it has bromine atom in place of methyl on 5' C base excision repair (BER) - repairs damaged base by using AP endonuclease to cleave damage on 5' side and DNA polymerase add new base...

BIO 315 Exam 1 Questions and Answers 100% Pass Humans have 23 pairs of chromosomes. Chromosomes 1-22 are best referred to as ______. a. Centromeres b. Autosomes c. Karyotype d. Nuclei e. Sex chromosomes - Correct Answer ️️ -B How many DNA molecules would be found in a single chromosome? a. 4 b. 10 c. More than 10 d. 1 e. 2 - Correct Answer ️️ -D An alternate form of a gene is called a(n) ________. a. Allele b. Exome c. Genome d. Chromosomes e. mutation - Correct Answer...

1.A0006 Treat recurrent Clostridium difficile toxin-induced diarrhea Correct answer-D/c causative antibiotic Metronidazole 10-14 days (pts w/ mild disease, absent/minimal systemic symptoms) Oral vanc: severe disease, metronidazole intolerance, pregnant Recheck diagnostic studies after each relapse to confirm C.diff is still causative etiology 1st relapse: 2nd course of original antibiotic (assuming similar severity of disease) Total colectomy → fulminant colitis w/ perforation or toxic me...

In cells which express telomerase, telomerase will add telomeric sequences to: - ️️The 3' ends of chromosomes A missense mutation is ... - ️️A mutation that changes the amino acid encoded Generally speaking, the genes for regulatory proteins that directly detect environmental signals (for example, the Lac Repressor protein) are transcribed... - ️️All the time (constitutively) The coding region for the lacZYA operon is fused to a strong, constitutively expressed eukaryotic p...

Which level of protein structure is disrupted through the hydrolysis of peptide bonds? Quaternary Tertiary Primary Secondary - Primary The primary structure of a protein is the sequence of amino acids held together by peptide bonds. Peptide bonds are formed by dehydration reactions and disrupted by hydrolysis. A mutation in the beta-hemoglobin gene, which results in the replacement of the amino acid glutamate in position 6 with the amino acid valine, leads to the development of...