Coagu - Study guides, Class notes & Summaries

Fibrinogen Substrate Stable Liver Non-Vitamin K dependent Consumed during clotting Correct Answer: Factor I Prothrombin Serine protease Stable/Variable Liver Vitamin K dependent Consumed during clotting Correct Answer: Factor II Proaccelerin Cofactor Labile Liver Non-Vitamin K dependent Consumed during clotting Correct Answer: Factor V Proconvertin Serine Protease Stable Liver Vitamin K dependent Not consumed during clotting Correct Answer: Factor VII Anti-hem...

Anticoagulants are commonly used for ACS prevention of cardioembolic stroke prevention/treatment of VTE Venous thrombus embolism includes deep vein thrombosis Pulmonary embolism Factors that can lead to coagulation blood vessel injury blood stasis prothrombotic conditions Coagulation cascase can occur via these two pathways contact activation - intrinsic Tissue activation - extrinsic Contact activation pathway steps XII/XIIA->XI/XIA->IX/IXA->X/XA ...

NAPLEX Review – Anticoagulation Questions With Complete Solutions

Glucocorticoid mechanism of action (Ans- works to stop the inflammatory process in the lungs, preventing bronchoconstriction. Stabilizes WBC membranes that release bronchial constricting substances, increases bronchial smooth muscle beta adrenergic stimulation. Forms of Glucocorticoids (Ans- Inhaled: used for asthma and is the most tolerated and fast acting, but can also be IV for systemic effects on the body. AE of glucocorticoids (Ans- throat and mouth irritation, dry mouth, oral f...

A 50-year-old man has been on heparin for the past 7 days. Which combination of the tests is expected to be abnormal? APTT, TT only PT and APTT only APTT, TT, fibrinogen assay PT, APTT, TT - PT, APTT, TT A coagulation disorder commonly associated with umbilicus bleeding and post-circumcision bleeding is known as: Idiopathic thrombocytopenic purpura Glanzmann's thrombasthenia von Willebrand's disease Bernard-Soulier syndrome - Bernard-Soulier syndrome A decreased platelet count is m...

Coagulation Question and answers correctly solved Coagulation - CSMLS What are the requirements of normal blood flow? - correct answer smooth blood vessels allowing blood to escape in the surrounding tissues What is the timeline for vascular injury (after the sub endothelium is exposed) - correct answer 1-2 seconds: vessel constricts, PLTs adhere 10-20 seconds: PLT aggregate 1-3 minutes: PLT plug formed, reinforced with fibrin 3-5 minutes: PLT/fibrin plug contracts 5-10 minutes: ...

ANTICOAGULANTS AND THROMBOLYTIC AGENTS QUESTIONS WITH DETAILED ANSWERS

REVERSAL OF ANTICOAGULATION When an ICH occurs, the patient’s situation hinges on the balance between how great is the embolic risk while not receiving anticoagulants, and how big is the threat of the hemorrhage if the anticoagulant effect is not reversed promptly. The weighting of the two sides of this coin provides the rationale for deciding on the best treatment on a patient-by-patient basis. The evidence-based information about the most appropriate attitude regarding the O...

Anticoagulation BCPS – Questions & Proper Solutions