Cooperativity - Study guides, Class notes & Summaries
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UofSC BIO302 Exam 1- Stephanie Ackerson Questions And Answers Graded A+
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A - Alanine (1 letter) 
Activation of enzymes through ligand binding: why would this be useful? - The binding of a ligand 
to an allosteric site of a multimeric enzyme often induces positive cooperativity, that is the binding of 
one substrate induces a favorable conformation change and increases the enzyme's likelihood to bind to 
a second substrate. 
Ala - Alanine (3 letter) 
Arg - Arginine (3 letter) 
Asn - Asparagine (3 letter) 
Asp - Aspartic Acid (3 letter) 
Barr body and relation to heter...
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ACS Biochemistry Exam Questions and 
Correct Solutions 2024 
Describe the structural changes in hemoglobin that allow for cooperative binding of O2 - Answer - 
Binding of O2 in one subunit causes a conformational change in an adjacent subunit allowing O2 to bind 
Which amino acids in "a" would be charged at pH 7? - Answer -Asp, Glu, Arg, His, Lys 
Which amino acids are negatively charged? - Answer -Asp, Glu 
which amino acids are positively charged? - Answer -Arg, His, Lys 
How are beta sheets s...
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A Hill coefficient (nH) of 2 indicates that: 
A) there is positive cooperativity in ligand binding. 
B) there are two ligand-binding sites. 
C) there is negative cooperativity in ligand binding. 
D) there is positive cooperativity in ligand binding and there are two ligand-binding sites. 
E) there is negative cooperativity in ligand binding and there are two ligand-binding sites. - A) 
there is positive cooperativity in ligand binding. 
A monoclonal antibody differs from a polyclonal antibody in...
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You're using anion exchange chromatography to purify a small globular protein. After passing the mixture through the column, you find that your protein did not "stick" to the resin and flowed right through. What is a plausible reason for this to have occurred? Correct Answer-The pH of the solution is close to the isoelectric point. 
 
Oxygen binding that affects the cooperatively of hemoglobin is an example of heterotrophic regulation. Correct Answer-False 
 
You have determined that a leucin...
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E1: Why do proteins fold? - Answer A and B are correct (It is entropically favorable for 
water & It is enthalpically favorable for the protein) 
E1: The structural changes in hemoglobin that contribute toward its positive 
cooperativity for oxygen consist of: - Answer All of the above ( movement of iron into 
the plane of the heme & movement of a neighboring veiling residue due to strain from 
changes in the heme & the breaking of a covalent bond with the regulatory molecule 
BPG
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FTCE Biology Practice Exam Questions 
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During which phase of mitosis do tetrads form? 
a) prophase I 
b) prophase II 
c) metaphase I 
d) metaphase II - Correct Answer ️️ -a) prophase I 
The result of meiosis and cytokinesis is: 
a) two haploid (1n) cells 
b) four haploid (1n) cells 
c) two diploid (2n) cells 
d) four diploid (2n) cells - Correct Answer ️️ -b) four haploid (1n) cells 
What is the complementary sequence to this segment of DNA: 
5' CGTTAGGAATAC 3...
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Microfilament assembly is directional, in that there is a defined (-) and (+) end Correct Answer-A) True 
 
Cooperativity or allostery relates to Correct Answer-D) Quaternary strucuture 
 
How does the hydrophobic effect influence the structures of large molecules? Correct Answer-D) A and B 
 
a- nonpolar groups are not easily solubilized in water and aggregate 
b- polar groups are oriented on the surface, interacting with the water 
 
An exergonic process is spontaneous Correct Answer-A) True 
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Prophase I (Meiosis) CORRECT ANSWER During which phase of meiosis do tetrads form? 
 
4 haploid cells CORRECT ANSWER What is the end result of meiosis and Cytokinesis? 
 
The first step in gene expression CORRECT ANSWER Transcription of DNA into a molecule of mRNA 
 
At the G2 checkpoint, damaged DNA that cannot be fixed will initiate a cellular, self-destruct process called: CORRECT ANSWER Apoptosis 
 
The activity of an ezyme could be regulated by: CORRECT ANSWER Feedback Inhibition 
Positive ...
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FTCE Biology Practice Exam Questions 
with 100% Correct Answers 
During which phase of mitosis do tetrads form? 
a) prophase I 
b) prophase II 
c) metaphase I 
d) metaphase II - Correct Answer ️️ -a) prophase I 
The result of meiosis and cytokinesis is: 
a) two haploid (1n) cells 
b) four haploid (1n) cells 
c) two diploid (2n) cells 
d) four diploid (2n) cells - Correct Answer ️️ -b) four haploid (1n) cells 
What is the complementary sequence to this segment of DNA: 
5' CGTTAGGAATAC 3...
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Ways of regulating enzymes - ANSWER-allosteric effector 
competitive inhibition 
noncompetitive inhibition 
cooperativity 
 
Competitive inhibition - ANSWER-substance the enzyme by occupying the active site 
 
Noncompetitive inhibition - ANSWER-substance inhibits the enzyme by binding to a location other than the active site and changes the shape of the enzyme 
 
Cooperativity - ANSWER-enzyme becomes more receptive to additional substrates 
 
Ribosomes are manufactures in the... - ANSWER-nucleus...
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