Denosumab Study guides, Class notes & Summaries
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![WGU D236 Objective Assessment Pathophysiology Exam (Latest 2023/ 2024 Update) Questions and Verified Answers| Grade A](/docpics/3527899/65172cd3b16b7_3527899_121_171.jpeg)
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WGU D236 Objective Assessment Pathophysiology Exam (Latest 2023/ 2024 Update) Questions and Verified Answers| Grade A
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WGU D236 Objective Assessment Pathophysiology Exam (Latest 2023/ 2024 Update) Questions and Verified Answers| Grade A 
 
Q: What is Spina Bifida? Why are relative deficiencies in Folic acid or B12 associated with Spina Bifida? 
 
Answer: 
 Failure to close the neural tube early in gestation due to low folic acid and B-12 These vitamins help activate DNA synthesis in the developing fetus in the first 4 weeks of pregnancy, that are responsible for closing up the spinal column. Three types of spina...
![WGU D236 PATHOPHYSIOLOGY FINAL EXAM 300+ REAL EXAM QUESTIONS AND VERIFIED ANSWERS WITH RATIONALES LATEST UPDATE 2023](/docpics/3010590/64a4307914f9e_3010590_121_171.jpeg)
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WGU D236 PATHOPHYSIOLOGY FINAL EXAM 300+ REAL EXAM QUESTIONS AND VERIFIED ANSWERS WITH RATIONALES LATEST UPDATE 2023
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WGU D236 PATHOPHYSIOLOGY 
FINAL EXAM 300+ REAL EXAM 
QUESTIONS AND VERIFIED 
ANSWERS WITH RATIONALES 
LATEST UPDATE 2023 
Describe how your body responds to an infection. - ANSWER- T cells produce 
cytokines, which stimulate B cells. B cells produce antibodies. 
Identify role of DNA changes in congenital abnormalities. - ANSWERMutations in genes or chromosomal abnormalities 
How does development disrupts congenital abnormalities? - ANSWERAlterations of DNA 
Describes factors that disrupt homeo...
![Chapter 30: Drug Therapy for Osteoporosis, Arthritis, and Skeletal Muscle Relaxation Workman & LaCharity: Understanding Pharmacology: Essentials for Medication Safety, 2nd Edition](/docpics/62eae8278559d_1881579.jpg)
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Chapter 30: Drug Therapy for Osteoporosis, Arthritis, and Skeletal Muscle Relaxation Workman & LaCharity: Understanding Pharmacology: Essentials for Medication Safety, 2nd Edition
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1. Which process replaces new bone cells within bone to keep the bone dense? 
a. Osteoporosis 
b. Osteoblastic activity 
c. Osteoclastic activity 
d. Bone resorption of calcium 
ANS: B 
Osteoblastic activity is the replacement of new bone cells within an existing bone. 
Osteoclastic activity removes bone cells. Osteoporosis is the imbalance between osteoblastic 
activity and osteoclastic activity that results in decreased bone density. Bone resorption of 
calcium is the REMOVAL of calcium from b...
![WGU pathophysiology D236-Exam Questions and Answers 2022-2023](/docpics/6387157d562e3_2143913.jpg)
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WGU pathophysiology D236-Exam Questions and Answers 2022-2023
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WGU pathophysiology D236-Exam Questions and Answers 2022/2023 
 
What is Starling's Law of Capillary forces? 
 
How does this explain why a nutritionally deficient child would have edema? - ANSWER Starling's Law describes how fluids move across the capillary membrane. There are two major opposing forces that act to balance each other, hydrostatic pressure (pushing water out of the capillaries) and osmotic pressure (including oncontic pressure, which pushes fluid into the capillaries). 
 
Bot...
![NURS 5334 / NURS5334 ADVANCED PHARMACOLOGY EXAM 3 STUDY GUIDE. QUESTIONS WITH ANSWERS.](/docpics/62f957c87a90f_1898209.jpg)
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NURS 5334 / NURS5334 ADVANCED PHARMACOLOGY EXAM 3 STUDY GUIDE. QUESTIONS WITH ANSWERS.
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Raloxifene-SERM 
Structurally like estrogen and binds to estrogen receptors 
Adverse effects 
• Thromboembolic events, such as deep vein thrombosis (DVT), pulmonary embolism, stroke, and fetal harm 
Teriparatide 
—form of PTH; increases bone formation 
Indications: osteoporosis in postmenopausal women, treatment of osteoporosis in men, treatment of glucocorticoid-induced osteoporosis 
 
Denosumab 
—receptor activator of nuclear factor kappa-B ligand (RANKL) 
Osteoporosis in postmenopausal ...
![ABFM Questions (Adult) with complete solutions 2024/2025](/docpics/5027024/661f966e4f90e_5027024_121_171.jpeg)
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ABFM Questions (Adult) with complete solutions 2024/2025
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ABFM Questions (Adult)Side effect of denosumab and bisphosphonates - correct answer Jaw osteonecrosis 
 
Most likely to induce remission in Crohn dz - correct answer corticosteroids > 5-ASA > infliximab 
 
Bisphosphonates shouldn't be used in pts w/CLCr less than - correct answer 35 mL/min/1.73m2 
 
Bisphosphonates use for 5+ years risks... - correct answer atypical femoral shaft fractures, recommend drug holiday 
 
Denosumab is safe in CKD because - correct answer not cleared b...
![ABFM Questions (Adult) 2024 With Complete Solutions](/docpics/4816858/65fe6dc999e04_4816858_121_171.jpeg)
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ABFM Questions (Adult) 2024 With Complete Solutions
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ABFM Questions (Adult) 2024 With Complete Solutions 
 
 
Side effect of denosumab and bisphosphonates - ANSWERSJaw osteonecrosis 
 
Most likely to induce remission in Crohn dz - ANSWERScorticosteroids > 5-ASA > infliximab 
 
Bisphosphonates shouldn't be used in pts w/CLCr less than - ANSWERS35 mL/min/1.73m2 
 
Bisphosphonates use for 5+ years risks... - ANSWERSatypical femoral shaft fractures, recommend drug holiday 
 
Denosumab is safe in CKD because - ANSWERSnot cleared by kidneys 
 
IB...
![Chemotherapy Test Study Questions & Answers(RATED A+)](/docpics/4298435/65ae7b3c6082f_4298435_121_171.jpeg)
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Chemotherapy Test Study Questions & Answers(RATED A+)
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True or False? Bevacizumab blocks angiogenesis and is therefore associated with quicker wound healing. - ANSWER False 
 
True or False? Cetuximab is associated with acneform rash, which may lead to delay in doses or discontinuation of the drug for recurrent episodes. - ANSWER True 
 
True or False? Denosumab is used to prevent skeletal-related events due to bone mets from solid tumors. - ANSWER True 
 
True or False? Denosumab can be used in managing skeletal-related events due to multiple myelo...
![ABFM questions and answers already passed 2024](/docpics/4954188/6614b06246b96_4954188_121_171.jpeg)
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ABFM questions and answers already passed 2024
- Exam (elaborations) • 48 pages • 2024
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ABFM questions and answers already passed 2024 Side effect of denosumab and bisphosphonates - correct answer Jaw osteonecrosis 
 
Most likely to induce remission in Crohn dz - correct answer corticosteroids > 5-ASA > infliximab 
 
Bisphosphonates shouldn't be used in pts w/CLCr less than - correct answer 35 mL/min/1.73m2 
 
Bisphosphonates use for 5+ years risks... - correct answer atypical femoral shaft fractures, recommend drug holiday 
 
Denosumab is safe in CKD because - corre...
![WGU D236 PATHOPHYSIOLOGY LATEST ACTUAL EXAM 2023/2024 260 QUESTIONS AND CORRECT ANSWERS](/docpics/3114343/64bcc6d31c407_3114343_121_171.jpeg)
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WGU D236 PATHOPHYSIOLOGY LATEST ACTUAL EXAM 2023/2024 260 QUESTIONS AND CORRECT ANSWERS
- Exam (elaborations) • 52 pages • 2023
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WGU D236 PATHOPHYSIOLOGY LATEST ACTUAL EXAM 2023/2024 260 QUESTIONS AND CORRECT ANSWERS 
How does denosumab treat osteoporosis? - ANSWER-Denosumab is an antibody that slows down the natural rate your bones are broken down. It works by blocking a protein and suppressing the cells that break down bone.
![Chemotherapy Test Study Questions and Answers(RATED A)](/docpics/4301593/65aece8729af5_4301593_121_171.jpeg)
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Chemotherapy Test Study Questions and Answers(RATED A)
- Exam (elaborations) • 20 pages • 2024
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Chemotherapy Test Study Questions and Answers(RATED A) 
 
True or False? Bevacizumab blocks angiogenesis and is therefore associated with quicker wound healing. - ANSWER False 
 
True or False? Cetuximab is associated with acneform rash, which may lead to delay in doses or discontinuation of the drug for recurrent episodes. - ANSWER True 
 
True or False? Denosumab is used to prevent skeletal-related events due to bone mets from solid tumors. - ANSWER True 
 
True or False? Denosumab can be used...
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