Doacs - Study guides, Class notes & Summaries

VTE TREATMENT: DOACS EXAM 2024/2025

VTE TREATMENT: DOACS EXAM 2024/2025

Based on the readings, which DOAC has the shortest half-life yet is dosed once daily? A. Apixaban B. Rivaroxaban C. Dabigatran C All the DOACs have a short onset of action; however, which two require "bridging" with a parenteral anticoagulant for the treatment of DVT/PE? A. Dabigatran and rivaroxaban B. Dabigatran and apixaban C. Dabigatran and edoxaban D. None of the DOACs require bridging B At what degree of hepatic dysfunction should rivaroxaban be avoided? A. Child-Pugh...

Limitations of warfarin - Answer Requires routine INR monitoring Frequent dose adjustments Has many interactions Delayed onset - often requiring concomitant parenteral anticoagulant Benefits of warfarin - Answer Established monitoring assay (can establish if patient is under or over coagulated - doesn't exist for DOACs) Extensive clinical experience No dosage adjustment for renal dysfunction (DOACs do) More experience with reversal agents Inexpensive 2 types of D...

ESOP Pharmacology: DOACs questions with correct answers

MOA of DOACs - Answer direct factor Xa inhibitor MOA of dabigatran - Answer direct thrombin inhibitor dosing of dabigatran for VTE - Answer usual: 150 mg PO BID after 5-10 days of injectable anticoagulant renal: contraindicated if CrCl <30 ml/min monitoring for dabigatran - Answer no lab tests are necessary due to predictable dose response -might be necessary when life-threatening bleeding or prior to emergent surgery: PTT efficacy of dabigatran - Answer -no lab ...

Direct acting oral anticoagulants (DOACs) questions with correct answers

Anticoagulation (warfarin, DOACs, heparins, direct thrombin inhibitors) questions with correct answers

Direct Oral Anticoagulants (DOACs) & Thrombus Formation

DOACs questions with correct answers