Gms6504 exam 1 questions - Study guides, Class notes & Summaries

GMS6504 Exam 1 Questions and answers

GMS6504 Exam 1 Questions And Answers Rated A+ Which of the following would best be described as a system independent parameter determining pharmacological response? Receptor affinity for the ligand When taking a natural agonist and converting it to an antagonist using synthetic chemistry, what are the desired effects on affinity and efficacy? Affinity increases, efficacy decreases In the Langmuir equation, which variable represents the proportion of receptors that are bound by ligand? Kd ...

GMS6504 Review Exam 1 Problem Set 1: Intro, Receptors, and Response Questions With Complete Solutions

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GMS6504 Exam 2 Questions And Answers With Real Tests What are the 4 things that make something a good drug? ANS 1. Lipinski's Rule of 5 2. Chemical reactivity: good or bad? 3. Some chemically or biologically reactive functional groups to recognize 4. Choosing a target What is Lipinski's Rule of 5? ANS 1.Molecular mass greater than 500 Da 2.High lipophilicity (expressed as LogP greater than 5) 3.More than 5 hydrogen bond donors 4.More than 10 hydrogen bond acceptors Par...

GMS6504 Review Exam 1 Problem Set 1-3 Pharmacological Assays Questions And Answers Which of the following would best be described as a system independent parameter determining pharmacological response? The number of receptors present The cellular cascade Pharmacokinetics Receptor affinity for the ligand Presence of an antagonist Receptor affinity for the ligand When taking a natural agonist and converting it to an antagonist using synthetic chemistry, what are the desired effects on af...