Pmy 302 - Study guides, Class notes & Summaries

Desmopressin MOA - activates V2 receptors in the kidney's collecting ducts, reabsorbing water into plasma and concentrating the urine (prevents water from leaving the body) Octreotide Acetate and Lanreotide Therapeutic effects - suppresses GH hypersecretions, reduces pituitary adenoma overgrowth, and normalizing levels of GH and IGF-1 Somatropin Drug Class - Synthetic recombinant human growth hormone Somatropin/Somatrem dosing - Daily dosing dependent and adjusted to individual clinical r...

principal determinants of BP - arterial pressures (CO X peripheral resistances) and Cardiac outputs (heart rate, myocardial contractility, blood volumes and venous returns) life style modifications available to tx hypertension - weight loss, sodium regulations, DASH diets, alcohol restriction, aerobic exercises and smoking cessation consequences of hypertension - myocardial infarction, heart failure and angina development, kidney disease risk, stroke and arterial pressure rising hypertensi...

Monoamine Oxidase Inhibitors (MAOIs) - Antidepressant Inhibit activity of MAOs to stop them from breaking down 5HT, NE in synapse and stores, irreversible, takes a few weeks to replace Side effects: Bad reaction with tyramine rich foods "wine-cheese interaction" fatal (MAO-A drugs only) Meperidine (Demerol) - Strong opioid agonist Uses: Preoperative medication, acute pain, child birth Short duration of action, only used in codeine allergic patients Chlorpheniramine - antihistamine 1st ...

therefore, increase CO but doesn't change BP bc not much effect on B2 albuterol - B-AR agonist Affinity: B2>>>> B1 Examples of drug/food- drug interactions in Type A ADRS - viagra and nitrates - severe hypotension warfarin and heparin - bleeding alcohol and acetaminophen - increase CYP2E1 toxin grapefruit - inhibits C450 which inc plasma drug conc Benadryl vs Advil PM minodoxil - treat hypertension but topically used for hair growth loniten vs rogaine Examples of Type A A...

PMY 302 Block 4 Exam (elaborations) Questions & answers | latest update version 2024 | Verified 100% Correct Explations | Already Passed Graded A+| Actual Complete Solution - DISTINCTION GUARANTEED

how do agonists binding to receptors alter cellular processes and cha/nge cellular phenotype - alter expression level of protein and the turnover number of the enzyme stereospecificity - most drugs are asymmetric (chiral or optically active); one stereoisomers binds with much greater affinity to the specific receptor pharmacology - study of all compounds that interact with the body pharmacodynamics - what a drug does to the body. Includes the molecular mechanisms by which a drug acts phar...

PMY 302 Introduction (exam 1) Study Guide with Complete Solutions

PMY 302 Block 1 Exam Study Guide with Complete Solutions

On Target ADR - Warfarin is an example. This is a blood thinner so you are prone to stroke. It is doing what it's suppose to be doing, but because it thins your blood you are prone to stroke. (Doing what it should do, but too well maybe...adverse event due to therapeutic action of drug) Allergic Reaction - Nerve occurs on first response (because allergic reaction is a response built up by immune system, so upon first exposure to drug it does not have adverse response. but immune response u...