Tacrolimus - Study guides, Class notes & Summaries

The diagnostic evaluation can be used to classify acute kidney injury as prerenal, intrinsic renal, or postrenal. The initial workup includes a patient history to identify the use of nephrotoxic medications or systemic illnesses that might cause poor renal perfusion or directly impair renal function. Physical examination should assess intravascular volume status and identify skin rashes indicative of systemic illness. The initial laboratory evaluation should include measurement of serum creatini...

Type A adverse drug reaction (ADR) -ANSWER- = predictable → dose-dependent + related to pharmacological actions of the drug Type B adverse drug reaction (ADR) -ANSWER- = unpredictable → NOT dose-dependent + can be influenced by patient-specific factors -allergies (immune mediated response) -pseudoallergic reactions (itching after opioid admin, vanco infusion reaction) -drug intolerances (N/V) -idiosyncratic reactions (SJS) Type I Reaction -ANSWER- → type of drug allergy ...

Midterm Exam: NR 568 (NR568) Advanced Pharmacology for the Adult-Gerontology Primary Care Nurse Practitioner Exam Review| Questions and Verified Answers |Latest 2023/ 2024- Chamberlain QUESTION True or false: Treatment for fungal Otitis Externa is: Ivermectin Answer: False: Treat- ment includes cleaning and application of acidifying drops; 2% acetic acid solution applied 3-4 times a day for 7 days. QUESTION How do you treat bacterial Otitis Externa? A. Topical Clotr...

Naplex things to remember correctly answered 2023CYP INHIBITORS *G PACMAN* Grapefruit Protease inhibitors (Ritonavir) Azole antifungals C - cyclosporine, cimetidine, cobicistat Macrolides (NOT azithromycin) Amiodarone (and dronedarone) Non-DHP CCBs CYP INDUCERS *PS PORCS* Phenytoin Smoking Phenobarbital Oxcarbazepine (and eslicarbazepine) Rifampin Carbamazepine (also auto-inducer) St. Johns wort Digoxin Levels 0.8-2 (Afib) 0.5-0.9 (HF) Toxicity: Initial ...

A nurse is providing teaching for a client who has received a liver transplant and has a prescription to transition from cyclosporine to tacrolimus. Which of the following instructions should the nurse include in the teaching? A. Take both the medications together for 72hr and then stop taking the cyclosporine B. Stop taking the cyclosporine for 24hr and then begin taking the tacrolimus C. Alternate taking the medications for 48hr and then take only the tacrolimus D. If adverse reactions to ...

12 month old male Past 3 months increased erythema and pruritus scratches all night, sheets bloody in the am family history of allergic rhinitis and asthma Answer Acute atopic dermatitis treatment for acute atopic dermatitis Answer Daily lukewarm bath 5-20min, mild or no soap. pat dry after bath, add emollient, ie. aquaphor Repeat emollient with each diaper change Topical steroids first line, least potent first calcineurini inhibitors to face (tacrolimus, and pimecrolimus) Consider...

Warfarin interactions - ANSWER-FLAMES o Fluconazole o Levofloxacin (really increase INR) o Amiodarone (worse interaction - decrease warfarin dose *by 50%*) o Metronidazole (decrease warfarin dose *by 1/3*) o Erythromycin (macrolides in general but this one is the worse) o Sulf-TMP CYP Inducers - ANSWER-PS PORCS o Phenytoin o Smoking o Phenobarbital o Oxcarbazepine (and eslicarbamazepine) o Rifampin o Carbamazepine (and its auto-inducer) o St. John's wort CYP Inhibitor...

12-month-old male Past 3 months increased erythema and pruritus scratches all night, sheets bloody in the am family history of allergic rhinitis and asthma - Acute atopic dermatitis treatment for acute atopic dermatitis - Daily lukewarm bath 5-20min, mild or no soap. pat dry after bath, add emollient, ie. aquaphor Repeat emollient with each diaper change Topical steroids first line, least potent first calcineurini inhibitors to face (tacrolimus, and pimecrolimus) Consider bleach baths a...

CPHON Exam 195 Questions with Verified Answers Classification of Methotrexate - CORRECT ANSWER antimetabolite (s-phase) Classification of mercaptopurine and thioguinine - CORRECT ANSWER antimetabolite(s-phase) Classification of fludarabine/nelarabine - CORRECT ANSWER anti-metabolite Classification of cytarabine/gemcitabine - CORRECT ANSWER antimetabolite Classification and sub-class of ironotecan/topotecan - CORRECT ANSWER Topoisomerase inhibitors (campotothecins) Classificatio...

CCTC Transplant pharmacology Exam 2024 Questions and Answers. Calcineurin inhibitors - Answer Cyclosporine or Sandimmune (Neoral, Gengraf) & Tacrolimus or hecoria (Prograf) MOA of Tacrolimus (Prograf) - Answer binds to fkbp12 to inhibit interleukin 2 production & release. Which inhibits cytotoxic T cells. MOA of Cyclosporine (Neoral, Gengraf) - Answer Binds to cyclophylin to inhibit interleukin 2 production & release. Which inhibits cytotoxic T cells. side effects of tacrolimus - Answer ...