PCEUT 531 2nd Midterm questions with correct answers

tablets - Answer solid dosage forms containing drug substances with or without suitable diluents and prepared either by compression or molding Compression - Answer large scale Molding - Answer small scale Compressed tablets - Answer prepared by single compression with no special coating (tableting machine exerts pressure, combining diluents, binders, fillers used to promote adhesion of particles) contain fillers and excipients done by punch and die method Multiple compressed tablet - Answer Made by more than one compression cycle; results in multilayered tablet (Purpose is 2-stage release of a drug that are incompatible like Hyzaar, Entex-PSE) Sugar Coated Tablet - Answer compressed tablet covered with a water soluble, usually colored sugar coat; protects drug from air and humidity and may help overcome objectionable drug taste (coating may be up to 50%) -- Dimetapp Film Coated Tablet - Answer compressed tablet covered with a thin water soluble polymer coating; durable coating (to mask taste) Bayer Aspirin Enteric Coated Tablet - Answer compressed tablet with a film coat that resists dissolution in acidic environment of the stomach; used to delay tablet