NAPLEX Practice Exam Questions exam Already Passed!!

Which of the following is true regarding niacin formulations? Answer A Niaspan is controlled-release niacin; it causes less flushing but more hepatotoxicity. B Niaspan is extended-release niacin; it causes less flushing and less hepatotoxicity. C Slo-Niacin is sustained-release niacin; it causes less hepatotoxicity but is the most expensive agent. D Slo-Niacin is interchangeable with other niacin formulations. E Niacin decreases both LDL and triglycerides and is one of the classes of drugs that does not cause hepatotoxicity. - B TR is beginning amiodarone therapy for new-onset atrial fibrillation. Which of the following statements is correct? Past Medical History: Heart failure Myocardial infarctions X 2 Hypertension Glaucoma Benign prostatic hypertrophy Medications:Lisinopril 20 mg PO daily Carvedilol 25 mg PO BID Aspirin 81 mg PO daily Lasix 40 mg PO daily Digoxin 0.25 mg PO daily Xalatan 1 drop QHS Proscar 5 mg PO daily Answer A Amiodarone is a p-glycoprotein inhibitor; the dose of digoxin should be decreased by up to 50%. B Amiodarone is a p-glycoprotein inducer; the dose of digoxin should be decreased by 25%. C Amiodarone is a CYP 3A4 inhibitor; the dose of digoxin should be increased by up to 50%. D Amiodarone should not be used in patients with heart failure. E Amiodarone is contraindicated in patients receiving digoxin. - A