BMTCN Review Chapter 1-Basic Concepts and Indications for Transplantation Q&A

BMTCN Review Chapter 1-Basic Concepts and Indications for Transplantation Goal of Transplant - ANSWER--Cure disease -Increase disease free survival Hematopoiesis - ANSWER--Regulation, production and development of blood cells -Pluripotent Stem cells -Progenitor Stem Cells. -Myeloid and lymphoid lineage Myeloid progenitor cells mature into: - ANSWER-Megakaryocytes (platelets) Erythrocytes Mast cells Myeloblasts Lymphoid progenitor cells mature into: - ANSWER-Small lymphocytes (B cells/T cells) Natural Killer Cells B cells - ANSWER--Develop in the bone marrow -Differentiate into plasma cells T-Cells - ANSWER--Further development in the thymus -T helper cells (type 1 and type 2) -T cytotoxic cells (T killer cells) -T suppressor cells Innate (Natura