Answers
Early Menopause Correct Ans ✓✓ FMP before age 45
Late Menopause Correct Ans ✓✓ FMP after age 54
Bilateral oophorectomy prior to age 45 increases risks for: Correct Ans
✓✓ - All cause mortality
- Coronary heart disease
- CVD
- Menopause symptoms
- Worsening mood symptoms
- Higher incidence of Parkinson Disease
- Associated with cognitive impairment
Early Menopause Transition (-2) Correct Ans ✓✓ 7 or more days
persistent difference in cycle length from previous normal cycle
- Results of increased follicular aging and depletion
- Inhibin B decreases
- FSH increases (Variable)
LOOP Cycles Correct Ans ✓✓ Explains elevation of Estradiol in
perimenopause
,- Rising FSH levels recruit 2nd follicle during luteal phase which leads
to overproduction of Estradiol
- This causes menstrual changes in future cycles
Decreased AMH in Early Menopause Transition Correct Ans ✓✓ More
frequent anovulatory cycles
Decreased Inhibin B in Early Menopause Transition Correct Ans ✓✓ -
Skipped menstrual cycles
- Mastalgia
- Migraine
- Menorrhagia (with LOOP cycles)
- Endometrial Hyperplasia
Late Menopause Transition (-1) Correct Ans ✓✓ 60 or more days of
amenorrhea for women aged 45 years or older
- Women 40-44 years with recurrent episodes of amenorrhea of 60 day
for longer within a year improves prediction of entry into late
menopause transition
Late Menopause Transition (-1) Duration Correct Ans ✓✓ 1-3 years
Late Menopause Transition (-1) Symptoms Correct Ans ✓✓ VMS
likely
, STRAW Stage where FSH > 25 Correct Ans ✓✓ Late Menopause
Transition (-1)
Elevated FSH symptoms in Late Menopause Transition Correct Ans ✓✓
- VMS
- Sleep disturbance
- Changes in weight distribution
- Increased variability in cycle length
Decreased Inhibin B in Late Menopause Transition Correct Ans ✓✓ -
Mood changes
- Cognitive complaints
- Changes in sexual functioning
- Increased prevalence of anovulation
Decreased AMH in Late Menopause Transition Correct Ans ✓✓ -
GSM
- Bone loss
- CVD issues
- Interval of amenorrhea > 60 days
POI Correct Ans ✓✓ Menopause before age 40