Immunology Module 4 practice test-
Graded A
Which of the following would be considered primarily organ specific autoimmune
disease?
-SLE
-RA
-Scleroderma
-Hashimoto's thyroiditis - ANSWER-Hashimoto's thyroiditis
A "butterfly rash" is a hallmark symptom of which autoimmune disease?
-Hishimoto's thyroiditis
-Grave's Disease
-RA
-SLE - ANSWER-SLE
The homogeneous ANA pattern is associated with which autoantibody?
Anti-SSA
Anti-ssDNA X
Anti-dsDNA
Anti-Jo - ANSWER-Anti ds DNA?
Which autoantibody is associated with Sjogren's syndrome?
Anti-SS-A
Anti-Jo
Anti-dsDNA
Anti-Sm - ANSWER-Anti-SS-A
Which of the following ANA patterns is associated with SLE?
Speckled
Nucleolar
, Peripheral
Homogeneous - ANSWER-Homogeneous
Anti-phospholipid antibody may be produced by SLE patients. How does this antibody
interfere with laboratory testing?
Causes a falsely elevated alkaline phosphatase result
Causes a false decrease in RBC indices
Causes prolonged PT/PTT
Causes false positive RPR tests - ANSWER-Causes prolonged PT/PTT
Anti-cardiolipin antibody produced by some patients with SLE will interfere with which
laboratory test(s)?
PT/PTT
RPR/VDRL
FTA-ABS for Treponema pallidum antibodies
Rheumatoid factor tests - ANSWER-RPR/VDRL
Anti-Sm anti-nuclear antibody is associated with which ANA pattern?
Speckled
Nucleolar
Peripheral
Homogeneous - ANSWER-Speckled
The Lupus anticoagulant is also known as:
Anti-phospholipid antibody
Rheumatoid factor
Anti-cardiolipin antibody
Graded A
Which of the following would be considered primarily organ specific autoimmune
disease?
-SLE
-RA
-Scleroderma
-Hashimoto's thyroiditis - ANSWER-Hashimoto's thyroiditis
A "butterfly rash" is a hallmark symptom of which autoimmune disease?
-Hishimoto's thyroiditis
-Grave's Disease
-RA
-SLE - ANSWER-SLE
The homogeneous ANA pattern is associated with which autoantibody?
Anti-SSA
Anti-ssDNA X
Anti-dsDNA
Anti-Jo - ANSWER-Anti ds DNA?
Which autoantibody is associated with Sjogren's syndrome?
Anti-SS-A
Anti-Jo
Anti-dsDNA
Anti-Sm - ANSWER-Anti-SS-A
Which of the following ANA patterns is associated with SLE?
Speckled
Nucleolar
, Peripheral
Homogeneous - ANSWER-Homogeneous
Anti-phospholipid antibody may be produced by SLE patients. How does this antibody
interfere with laboratory testing?
Causes a falsely elevated alkaline phosphatase result
Causes a false decrease in RBC indices
Causes prolonged PT/PTT
Causes false positive RPR tests - ANSWER-Causes prolonged PT/PTT
Anti-cardiolipin antibody produced by some patients with SLE will interfere with which
laboratory test(s)?
PT/PTT
RPR/VDRL
FTA-ABS for Treponema pallidum antibodies
Rheumatoid factor tests - ANSWER-RPR/VDRL
Anti-Sm anti-nuclear antibody is associated with which ANA pattern?
Speckled
Nucleolar
Peripheral
Homogeneous - ANSWER-Speckled
The Lupus anticoagulant is also known as:
Anti-phospholipid antibody
Rheumatoid factor
Anti-cardiolipin antibody