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psyo-1011-sept-18th-lecture-notes-4

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  • November 17, 2022
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Psyo 1011 - Sept. 18th - Lecture notes 4


Intro to Psyo & Nesc I (Dalhousie University)




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Sept. 18th
 Ions move across the membrane through channels because of 2
different physical forces, electrical forces and osmotic forces.
 Both these forces act on the ions inside and outside of the
neuron.
 The electrical force pushes potassium in and the chemical force
pushes it out and since the chemical/ osmotic force is stronger,
the net force is out of the cell.

 The equilibrium potential is the membrane potential at which the
electrical and osmotic/chemical forces are balanced and there’s
no net flow of ions across the membrane.

 It can be used to find which direction the ion is going to move and
to know what’s going to happen as soon as the channel opens.

 The equilibrium potential for sodium is +65mV

 The resting potential should shift to the equilibrium potential for
the movement of ions to stop and the net movement becomes
zero.

 The concentration of K+ outside a typical neuron is reduced by ½.
The K+ ions will move outside the cell. This makes the equilibrium
potential more negative as the osmotic force becomes stronger.

 When you open the channel for a particular ion, the resting
potential will move towards the equilibrium potential of that
particular ion.

 If the concentration of K+ outside the cell is more, the osmotic
force will be weaker so the equilibrium potential will be more
positive.



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