Class notes

Bio 1A03 - T2M2 to T3M2 Notes - Lectures and Modules

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Course
BIO1A03

Institution
McMaster University (mcmasteru)

An in-depth package of notes for Bio 1A03 from T2M2, T2M3, T2M4, T3M1, and T3m2. Notes include pictures and easy-to-follow notes from the module and lectures. The topics include: Prokaryotic Gene Regulation Levels of regulations Transcriptional modifications The Operon Model Negative Regula...

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Uploaded on February 25, 2023
Number of pages 2
Written in 2022/2023
Type Class notes
Professor(s) Dr. kajiura and dr. da silva
Contains T2m2 - t3m2

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● The Genetic Code

○ Proteins are made from 20 Nucleotides

● Defining a Codon

○ Glasow stated that the Nucleotides must be in 3 base codes

■ Multiple unique triplets would code for the same Amino Acid

● Deciphering the Code

○ Researchers took simple mRNA proteins and saw what they coded for

○ Marshall Nerenberg and Johann Mattaei

■ All the components they believed were necessary for Protein synthesis

into tubes

● RNA Template, nucleotides, Ribosomes, Amino acids, and an

energy source

■ Started by making a simple Nucleic acid made of Uracils

● Produced a repeating simple polypeptide sequence - identical

amino acids

○ Created Phenylalanine

■ Follow up research used alternating Uracil and Cytosines

●

● Always resulted in a string of Leucine and Serine

● Confirmed 3 nucleotides result in a Codon

● The standard code

○ Codons are written 5’ to 3’ position

■ Codons on the coding strand = non-template strand

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