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Epidemiology and Toxicology

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What is epidemiology? - It is a diagnostic discipline of public health. It is the study of factors that modify or influence the distribution of diseases (or of adverse health effects) in a human population. What are some vital functions of epidemioloy? - 1. to discover the agent, host and env...

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  • August 3, 2023
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  • 2023/2024
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Epidemiology and Toxicology


What is epidemiology? - It is a diagnostic discipline of public health. It is the study of factors that modify
or influence the distribution of diseases (or of adverse health effects) in a human population.



What are some vital functions of epidemioloy? - 1. to discover the agent, host and environmental
factors which affect health

2. determine relative importance of various causes of disease

3. identify high risk population

4. evaluate effectiveness of current programs, services and regulations



What is health risk assessment? - The process by which the potential adverse health effects of human
exposure to etiologic agents (chemicals) are characterized



What are the three health risk assessment components? - 1. Hazard identification- looking at risk to our
health and assessing it, identify what is a hazard and what isn't

2. Dose-response assessment -

3. Exposure assessment - need to know who is exposed and what the exposure level is in our
environment



Which type of product is given the lowest risk by people? - If hazard is controllable and observable,
people give it the lowest risk



Quantify the differences observed when switching from animal to human model? - 10-fold difference in
terms of kinetics and dynamics from animals to humans, then from humans to another human, due to
genetic variability another 10 fold difference



When did the concept of epidemiology start? - With the Black death --> fleas on rats

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