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Myocardial Infarction
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Necrosis - tissue death Myocardial Infarction definition: - The development of ischemia with resultant necrosis of the myocardium caused from prolonged obstruction of the coronary arteries depriving the heart muscle of oxygen Importance of oxygen in the body - reduces acidity When do...

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  • August 3, 2023
  • 6
  • 2023/2024
  • Exam (elaborations)
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Myocardial Infarction


Necrosis - tissue death



Myocardial Infarction definition: - The development of ischemia with resultant necrosis of the
myocardium caused from prolonged obstruction of the coronary arteries depriving the heart muscle of
oxygen



Importance of oxygen in the body - reduces acidity



When do most MI occur - between thanksgiving and new years because of all of the stress



Acute Myocardial infarction caused by - sudden thrombotic occulusion of a coronary artery



Acute Myocardial infarction occurs - at the site of an atherosclerotic plaque that has become unstable
due to a combination of ulceration, fissuring and rupture.



thrombosis - blood clot composed of platelets



Congestive heart failure occurs 25% of the time when - left ventricle is infarcted



ST-Segment Elevation is indicative of - MI



ST-Segment depression is indicative of - ischemia and angina



Most patients who sustain an MI have - coronary atherosclerosis.



A thrombus can become a - embolus

, Plaque rupture is believed to be the triggering mechanism for the development of a - thrombus



The thrombus formation occurs most often at the site of an - atherosclerotic lesion, thus obstructing
blood flow to the myocardial tissues.



80 - 90% of all MIs are derived from a - coronary thrombus



People with diabetes are more prone to - thrombus/embolus



What happens to a part of the body when ischemic? - inflammatory reaction, edema, platelet
aggregation, necrosis



Myocardium receives its blood supply from - 2 large coronary arteries and their branches



Most common site of MI - Left ventricle



Zone of infarction - region of ischemic damage



Ischemia and reperfusion injury is accompanied by an inflammatory response



Immediately surrounding the zone of infarction is a region called the - zone of hypoxic injury



What zone is reversible if blood perfusion is reestablished - Zone of Ischemia



MIs can be located in the - anterior, septal, lateral, posterior, or inferior walls of the left ventricle.



What factors determine the size of the resulting MI? - extent or severity of the ischemic episode, size of
vessel, amount of circulation, vascular tone, metabolic demands of the myocardium

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