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Solutions for Biochemistry, 7th Edition by Garrett Grisham

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  • Course
  • Biochemistry
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  • Biochemistry

Complete Solutions Manual for Biochemistry 7e 7th Edition by Charles M. Grisham, Reginald H. Garrett. Full Chapters Solutions are included - Chapter 1 to 32 Part I: MOLECULAR COMPONENTS OF CELLS. 1. The Facts of Life: Chemistry is the Logic of Biological Phenomena 1. 2. Water: The Medium of Li...

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  • October 6, 2023
  • 979
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
  • Biochemistry
  • Biochemistry
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Biochemistry,
7th Edition




Reginald H. Garrett

University of Virginia

Charles M. Grisham

University of Virginia




Instructor Solutions Manual, Study
Guide, and Problems Book
included in document.

,Table of Contents

Preface

Chapter 1 - The Facts of Life: Chemistry Is the Logic of Biological Phenomena

Chapter 2 - Water: The Medium of Life

Chapter 3 - Thermodynamics of Biological Systems

Chapter 4 - Amino Acids and the Peptide Bond

Chapter 5 - Proteins: Their Primary Structure and Biological Functions

Chapter 6 - Proteins: Secondary, Tertiary, and Quaternary Structure

Chapter 7 - Carbohydrates and the Glycoconjugates of Cell Surfaces

Chapter 8 - Lipids

Chapter 9 - Membranes and Membrane Transport

Chapter 10 - Nucleotides and Nucleic Acids

Chapter 11 - Structure of Nucleic Acids

Chapter 12 - Recombinant DNA: Cloning, Chimeric Genes, and Synthetic Biology

Chapter 13 - Enzymes—Kinetics and Specificity

Chapter 14 - Mechanisms of Enzyme Action

Chapter 15 - Enzyme Regulation

Chapter 16 - Molecular Motors

Chapter 17 - Metabolism: An Overview

Chapter 18 - Glycolysis

Chapter 19 - The Tricarboxylic Acid Cycle

Chapter 20 - Electron Transport and Oxidative Phosphorylation

Chapter 21 - Photosynthesis

,Chapter 22 - Gluconeogenesis, Glycogen Metabolism, and the Pentose

Phosphate Pathway

Chapter 23 - Fatty Acid Catabolism

Chapter 24 - Lipid Biosynthesis

Chapter 25 - Nitrogen Acquisition and Amino Acid Metabolism

Chapter 26 - Synthesis and Degradation of Nucleotides

Chapter 27 - Metabolic Integration and Organ Specialization

Chapter 28 - DNA Metabolism: Replication, Recombination, and Repair

Chapter 29 - Transcription and the Regulation of Gene Expression

Chapter 30 - Protein Synthesis

Chapter 31 - Completing the Protein Life Cycle: Folding, Processing, and Degradation

Chapter 32 - The Reception and Transmission of Extracellular Information

Glossary

, Chapter 1 The Facts of Life: Chemistry Is the Logic of
Biological Phenomena
•••••••••••••••••••••••••

Chapter Outline

• Properties of living systems
• Highly organized - Cells > organelles > macromolecular complexes >
macromolecules (proteins, nucleic acids, polysaccharides)
• Structure/function correlation: Biological structures serve functional purposes
• Energy transduction: ATP and NADPH –energized molecules
• Steady state maintained by energy flow: Steady state not equilibrium
• Self-replication with high, yet not perfect, fidelity

• Biomolecules
• Elements: Hydrogen, oxygen, carbon, nitrogen (lightest elements of the periodic
table capable of forming a variety of strong covalent bonds)
• Carbon -4 bonds, nitrogen -3 bonds, oxygen –2 bonds, hydrogen -1 bond
• Compounds: Carbon-based compounds –versatile
• Phosphorus- and sulfur-containing compounds play important roles

• Biomolecular hierarchy
• Simple compounds: H2O, CO2, NH4+, NO3–, N2
• Metabolites: Used to synthesize building block molecules
• Building blocks: Amino acids, nucleotides, monosaccharides, fatty acids, glycerol
• Macromolecules: Proteins, nucleic acids, polysaccharides, lipids
• Supramolecular complexes: Ribosomes, chromosomes, cytoskeleton

• Membranes: Lipid bilayers with membrane proteins
• Define boundaries of cells and organelles
• Hydrophobic interactions maintain structures

• Organelles: Mitochondria, chloroplasts, nuclei, endoplasmic reticulum Golgi, etc.

• Cells: Fundamental units of life
• Living state: Growth, metabolism, stimulus response and replication

• Properties of biomolecules
• Directionality or structural polarity
• Proteins: N-terminus and C-terminus
• Nucleic acids: 5’- and 3’- ends
• Polysaccharides: Reducing and nonreducing ends


Garrett & Grisham 1-1

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