100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
Introduction to Genetics (BIOL0003) Notes - Changes in Chromosomes CA$11.91   Add to cart
Quickly navigate to
Preview
  2.  
  3. University College London (UCL)
  4.  
  5. Introduction to Genetics (BIOL0003)

Class notes

Introduction to Genetics (BIOL0003) Notes - Changes in Chromosomes
 5 views  0 purchase
  • Course
  • Introduction to Genetics (BIOL0003)
  • Institution
  • University College London (UCL)

Explore the world of genetics with these concise notes tailored for Year 1 students in the Introduction to Genetics (BIOL0003) module at University College London. This document focuses specifically on the dynamic topic of changes in chromosomes, encompassing alterations in chromosome number and st...

[Show more]

Preview 2 out of 6  pages

Document information

  • November 30, 2023
  • 6
  • 2020/2021
  • Class notes
  • Dr amanda cain
  • All classes

Subjects

  • chromosome
  • changes
  • changes in chromosome number
  • changes in chromosome structure

Written for

  • University College London (UCL)
  • Unknown
  • Introduction to Genetics (BIOL0003)
All documents for this subject (5)

Seller

avatar-seller
sujansathiendran

Reviews received

Content preview

Changes in Chromosome Number
Changes in Chromosome Number
 Aneuploidy – due to nondisjunction
o Formation of somatic cells
 Non-disjunction
 In meiotic division – failure of particular individual
chromosomes to go to the correct chromosome
end
o Results in sperm or egg with too many or
too few chromosomes
 Aneuploidy = presence of abnormal number of chromosomes in a cell
o Down’s syndrome
 Symptoms
 Short
 Breathing difficulty
 Narrow slanted eyes
 Trisomy 21
 Stain chromosomes in down syndrome child = extra
chromosome 21
o One of the smallest chromosomes
 Diagnostic test










 Egg production in females
o Mother makes all her eggs before birth – released during fertile period
 Released at later age – been in incomplete meiosis for longer =
increase in chromosomal abnormalities
 Translocation down’s syndrome
 Part of chromosome 21 has become attached to fathers sperm  attached to
another chromosomes  passed to another generation = leading to down’s
syndrome
 Mosaic down’s syndrome
 Patches of trisomy-21
o Non-disjunction took place early in development
 Individuals with mixtures of down’s chromosomes + normal chromosomes
 Prenatal diagnosis and termination

, Changes in Chromosome Number





 Sex chromosomes – x chromosome inactivation
o Klinefelter syndrome XXY
 Diploid sperm x haploid egg = XXY individual
 Diploid sperm – XY
 Haploid egg – X





o Turner syndrome XO
 O x X = XO individual
 Egg developed without a Y chromosome – O
 Haploid sperm – X





o Edwards syndrome
 Trisomy 18 – small chromosome
o Drosophila gynandromorph
 Non-disjunction in body cells
 Left side of animal is male – right side is female




o
o Sex determination in bees – haplodiploidy

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller sujansathiendran. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for CA$11.91. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

77764 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
CA$11.91
  • (0)
  Add to cart