Exam (elaborations)
Principles Of Pharmacology APRN – Q’s & A’s
Principles Of Pharmacology APRN – Q’s & A’s
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Principles Of Pharmacology APRN – Q’s & A’sPharmacodynamics ✔️Ans - drug receptor interaction and activity;
dose - response relationship
drug potency and efficacy
Receptors ✔️Ans - most drugs work by binding to what?
Reversible, selective, and graded ✔️Ans - drug receptor binding is ____, ____,
and ____
Pharmacologic response ✔️Ans - the more receptors filled by a drug, the
greater the what?
Toxicity; not produce pharmacological response ✔️Ans - drug response-
above the curve could cause what unwanted effect? below the curve means
the drug dose does not do what?
Onset of action ✔️Ans - time between administration and first sign of drug
effect
Peak of action ; equal ✔️Ans - maximum concentration of drug = ______ of
action; amt of drug being absorbed and distributed is 'what' to amt being
metabolized and excreted
Duration of action ✔️Ans - ______ of action: continued entry of drug into
body w/ levels above minimum effective concentration
Therapeutic Index or range ✔️Ans - MTC minus MEC =
Bioavailability ✔️Ans - percentage of drug that is absorbed and available to
reach target tissues is what?
To get to steady state blood levels and total elimination of drug from the body
✔️Ans - it takes 4 to 5 1/2 lives to get to what? and same for what?
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