Exam (elaborations)
WGU C785 Final 1 – Questions With Verified Solutions
WGU C785 Final 1 – Questions With Verified Solutions
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WGU C785 Final 1 – Questions With VerifiedSolutions
Which mRNA sequence results in a polypeptide that contains three amino
acids? ✔️Ans - 5' - CUU GAU ACU UAG - 3'
Which RNA sequence would end in the following polypeptide?
Phe-Thr-Val-Stop ✔️Ans - 5' - UUC ACA GUA UAA - 3'
What is the complementary sequence for the following DNA sequence?
5' - GCC ATC TCG AAT - 3' ✔️Ans - 5' - ATT CGA GAT GGC - 3'
Assuming 100% reaction efficiency, how many DNA copies are created after
the completion of four complete PCR cycles? ✔️Ans - 16
What is the function of DNA polymerase in the process of PCR? ✔️Ans - It
recognizes the primers and uses the available dNTPs to replicate the template
DNA sequence.
5' - [...] ATT CGC TAG GGC [...] - 3' − Normal DNA
5' - [...] ATT CGC GAG GGC [...] - 3' − Mutant DNA
Which type of mutation and outcome characterizes the Mutant DNA? ✔️Ans
- A missense mutation leading to a longer protein
In sickle-cell disease, the glutamic acid (Glu) at position number seven is
mutated to valine (Val).
What change in codons corresponds to this mutation? ✔️Ans - GAA to GTA
What are possible blood types of the parents of a patient with blood type AB?
✔️Ans - A and B
Which pair of chromosomes accurately depicts the genotype of a person with
an autosomal recessive mutant HBB allele and sickle cell anemia? ✔️Ans -
option 3- 2 mutant genes on chromosome 11
, Which pair of chromosomes accurately depicts the genotype of a person with
an X-linked recessive mutant ALAS2 allele and sideroblastic anemia? ✔️Ans
- option 3, mutated allele
Studies have shown that increased expression of two genes called SIRT1 and
SIRT2 is associated with chronic exposure to cocaine and contributes to drug
addiction.
What difference in the regions of the SIRT1 and SIRT2 genes in people
addicted to cocaine increases their expression? ✔️Ans - The nucleosomes
become more widely spaced.
Mice with low levels of agouti gene expression tend to have yellow fur and are
obese, while mice with higher levels of expression are brown and of normal
weight. Studies show that expression of the agouti gene in mice can be
controlled by epigenetics.
Mice with low levels of agouti gene expression tend to have yellow fur and are
obese, while mice with higher levels of expression are brown and of normal
weight. Studies show that expression of the agouti gene in mice can be
controlled by epigenetics.
What scenario describes epigenetic regulation of the agouti gene? ✔️Ans -
Mother mice fed methyl-rich diets during pregnancy give birth to offspring
with decreased agouti gene expression compared to those fed a methyl-poor
diet.
Oxidative damage to DNA can often result in the alteration of a single
nucleotide.
Which DNA repair mechanism would repair this type of damage? ✔️Ans -
Base excision repair
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs when
one or more of the genes that perform nucleotide excision repair are
nonfunctional.
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