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UNE Medical Biochemistry Exam 1 Questions And Answers Graded A+
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UNE Medical Biochemistry Exam 1 Questions AndAnswers Graded A+
What percentage of water is in the body? ✅60%
Relationship between protons and acids & bases ✅acids donate proton. Bases accept
proton
Strong acids vs weak acids ✅strong acids fully dissociate (100%) and weak acids
partially dissociate
Properties of water ✅dipole dipole
Polar
H bonding
Dissolves electrolytes ( cl /na)
Small kd- doesn't dissociate alot
Kw ion product ✅10^-14
Ph ✅-log[h+]
Biological ph ✅7.4
Types of buffers ✅phosphates, bicarbonate, proteins
Buffers ✅weak acid and conjugate base
Ka ✅how well acid can dissociate
Pka ✅-log(ka)
50%dissociation
Buffers work best when? ✅ph=pka
Within +/- 1 ph unit of pka
Henderson-hasselbalch equation ✅ph= pka + log a-/ha
Ph<pka ✅protonated
Ph>pka ✅ionized
Amino acids are linked together by ✅peptide bonds between carboxyl and amino
group
, What's special about histidine pka? ✅close to biological ph of 7.4 so it can act as an
donor or acceptor
Nonpolar amino acids ✅glycine
Alanine
Proline
Valine
Leucine
Isoleucine
Aromatic amino acids ✅phenylalanine, tyrosine, tryptophan
Polar uncharged amino acids ✅asparagine
Glutamine
Serine
Threonine
Sulfur containing amino acids ✅methionine
Cysteine
Charged amino acids ✅aspartate
Glutamate
Arginine
Lysine
Histidine
Which 3 amino acids carry ammonia? ✅glutamine, glutamate, alanine
Which 3 amino acids can be phosphorylated? ✅serine, threonine, tyrosine
Pka of cooh and nh2 ✅2 and 9
What interactions can proteins have? ✅electrostatic forces
Dipole dipole
H bonding
Hydrophobic interactions
Alpha helix bonding ✅h bond between carbonyl o and amide 4 residues down
R groups stick out of helix
Hydrophobic core
Beta sheet bonding ✅h bonding between carbonyl o and amide across from each
other
R groups stick out
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