Class notes

Thermodynamics for Biochemistry - Biochemistry

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Course
MBB 222 (MBB222)

Institution
Simon Fraser University (SFU )

Condensed class notes for lectures about thermodynamics for biological sciences. Includes entropy, hydrophobic effects, protein folding , and Gibbs free energy.

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Uploaded on January 18, 2024
Number of pages 2
Written in 2023/2024
Type Class notes
Professor(s) Dustin king
Contains Class 2 to 3

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THER
MODYNAMICS

E
ANABOlic A

livinggEnergy Exciting
Arrosm is an in THAT o Can
open System

· Surroundings
master mod mos

AH
atzing
A could BE : =
Ein
System Enthalpy
-

I
A Brochemical RXN MEASURES How Much
-

Energy
is

PATHWAY REgUrrED By
-

A METABOLIC A
process .

Lost Heat
SSS & -

An individual cell AHO is Favourable

↳· ·
A WHOLE THE Of OH DETERMINED
By
-

VIVE
Organism
L
Is

·
8 ↑⑳
o -
S
-

of Bonds As
⑳
L

v
THE
N umber WELL As
--
·
Biods for BONd Types
Building
. MEASURED In JONES .

Biosynthesis

AS of Disorder AH <0
chang System LosEs HEA
=
Ein
Entropy Entropy is a Measure
-

OR RANDOMNESS "THE .
UNNERSE TENdS TOWArd CHAOS" An INCREASE
. In
Entropy is =
ExOTHERMIC

THERMODYNAMICALLY FAVOURABLE WHE A dECREASE In Enropy is Not . RECALL
MOLECUTES
NORPOLAR
IN WHER
AHO
SYSTEM TAKES HEAL from
of
Surrardnungs
WHEN A
SYSTEM RELEASES HEAT , i RANSES THE Entropy THE

=
Would Be of composer Endothermic
Surroundings
A SIMILAR CASE The

Aggreghrow
.

MOLECULES WATER : WHOLE THE is a decrease
Aggregation
In

... of the HO
↑ &

· surrounding
o
.
-
Evropy The
in morecues
· emropy
:
.
.....
②.... "no"
E
· ,

·

·
- 86 --- ....
%e

..........
...
-
g

:
INCREASES As MOTOw is LESS RESTRICTED

Biological Thermodynamics
folding
THERMODYNAMICS Of PROTEIN

·
·
Hydrophilic
·
Hydrophobic

proteins Hate
&

High
Evropy

[
WATER HAS LOW
Entropy
- Due To
Hydrophobic
Effects

SO S> E
WHER
PROTEINS

·mon
o· High Entropy
WATER Has

·
· ·
D
000
%
⑨
.00 .

⑧ ·o
· Proteins Have
· S Low
entropy

·
⑧

·...
&
o
o
·

-

- o
⑧

WATER AS7O PROTEINS ASSO

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