Exam (elaborations)
NU643 Week 4 Quiz 2 – Questions & Complete Answers
NU643 Week 4 Quiz 2 – Questions & Complete Answers
[Show more]
Content preview
NU643 Week 4 Quiz 2 – Questions & Complete AnswersTheories of schizophrenia. ✔️Ans - Elevations of dopamine, epigenetics
(genes being turned on and off due to environment), eNMDA/ glutamate
defective genes inherited- environmental pressures turn on defective genes
Mesocortical dopamine pathway ✔️Ans - Neg symptoms: 5 As alogia,
avolition, asociality, anhendonia, affective blunting, VTA to prefrontal
cortex: cognitive changes, slowing of thought (low levels of dopamine in
mesocortical pathway), drugs target this area to inc dopamine (because
there is less dopamine)
Tuberoinfundibular dopamine pathway ✔️Ans - inc prolactin, due to the
hypothamus, blocks dopamine, which in turn increases prolactin (inverse
relationship with dopamine (amenorrhea, galactorrhea (milk in breast)-
risperidone
Nigrostriatal dopamine pathway ✔️Ans - Movement disorders: tardive
dyskinesia, extrapyramidal symptoms, parkinsons's, slow brady-dyskinesia,
tremors
Mesolimbic dopamine pathway ✔️Ans - positive symptoms:
(hallucinations, rapid speech, delusions) hyperactivity in this pathway. The
mesolimbic pathway, sometimes referred to as the reward pathway, is a
dopaminergic pathway in the brain.
Conventional/typical antipsychotics ✔️Ans - haloperidol and
chlorpromazine (1st generation) tend to block dopamine D2 receptors in
all of the dopaminergic pathways of the brain.
atypical 2nd generations ✔️Ans - Less EPS, less movement disorders,
less side effects; Nonselectivity of receptor sites, serotonin (5HT) blocker
also (stimulates dopamine release further down in the brain), dopamine
blocker (dopamine is not blocked as fully as conventional antipsychotics)
EPS ✔️Ans - Caused by blocking of dopamine D2 receptors (risperidone
inc'd risk of EPS in high doses)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Studyhall. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for CA$13.02. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
80796 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now