Final Exam Review- AGACNP Spring 2023 Questions & Answers Updated 2024 .

Final Exam Review- AGACNP Spring 2023 Questions & Answers Updated 2024 .Oncologic Emergency- Hematologic- Febrile neutropenia and sepsis Febrile Neutropenia- Temp 100.4F and ANC 1000 Neutropenia + Infection = Emergency Considered sepsis until proven otherwise ... Sepsis = Most common cause of nonmalignant death Diagnosis Early recognition is key Think Sepsis Management Guidelines Q1H after first 60 minutes = 7.6 % increased mortality Obtain cultures PRIOR to treatment ! Treatment : Broad Spectrum ATB coverage Gram negative / positive coverage + MRSA PNA- atypical coverage until ruled out GI / enteric cause- Need GNB anaerobic coverage Consider antivirals / antifungals if a possible cause Oncologic Emergency- Hematologic- Hyperleukocytosis and Leukostasis Elevated WBC ( 100K ) Tissue damage occurs due to local hypoxia , hyperpermeability , and release of lysosomes and procoagulants Intravascular sludging and leukocytosis can develop along with white thrombus formation .