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Summary Cell and Molecular Biology - Cell and molecular biology 102 (Amb102) CA$12.75
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Summary Cell and Molecular Biology - Cell and molecular biology 102 (Amb102)

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I made the summary of replication from karp cell and molecular biology these notes help me to pass my exam as well as it help me to understand all the diagrams

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  • Replication
  • March 29, 2024
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  • 2023/2024
  • Summary
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DNA REPLICATION

, DEFINITION
• DNA replication is an enzymatic polymerization reactio
which DNA strand is used as a template to synthesize a c
with a base sequence that is complementary to the temp
Replication is semi conservative; each parent single stran
present in one of the double-stranded progeny molecules

, The original Watson-Crick proposal f
• The proposal for the structure of DNA replication of a double-helical molecu

by Watson and Crick in 1953 was
accompanied by a suggested
mechanism for its “self-duplication.”
• The two strands of the double helix are
held together by hydrogen bonds
between the bases.
• Individually, these hydrogen bonds
are weak and readily broken.
• Watson and Crick envisioned that
replication occurred by gradual
separation of the strands of the double
helix, much like the separation of two
halves of a zipper.

, • Semiconservative replication
• Because the two strands are
complementary to each other, each
strand contains the information
required for construction of the other
strand.
• Thus once the strands are
separated, each can act as a
template to direct the synthesis of
the complementary strand and
restore the double-stranded state.

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