Exam (elaborations)
2023 ATI Pharmacology Proctored Retake 1 Exam 70 QUESTIONS AND ANSWERS
- Course
- Institution
2023 ATI Pharmacology Proctored Retake 1 Exam 70 QUESTIONS AND ANSWERS
[Show more]
Seller
Follow
americannurse
Reviews received
Content preview
QUESTION 1. CYCLOOXYGENASE (COX-1, COX-2) Cyclooxygenase, an enzyme important for prostaglandin formation, abbreviated COX, has a form that we colloquially refer to as good COX and bad COX. Which cyclooxygenase is the “bad COX?” a) COX -1 b) COX -2 c) COX -3 d) COX -4 Answer B. Inhibiting or blocking COX -1, the good COX, can result in bad things: gastric erosion and ulcers, kidney impairment and bleeding. Suppresssing COX -2, the bad COX, can result in good things like suppressing inflammation, reducing pain and fever, and protecting against colon cancer. QUESTION 2. RESULTS OF BLOCKING COX -2 Drugs like ibuprofen, naproxen, and meloxicam affect cyclooxygenase. When we have inhibition of cyclooxygenase -2 (COX -2) we might expect all of the following except: a) Analgesia and antipyresis b) Colorectal cancer protection c) Gastric ulcers d) Suppressed inflammation C, Gastric ulcers. A gastric ulcer would likely result from blocking the good COX, COX -1. However, if we block COX -2, the bad COX, we get analgesia (pain reduction), antipyresis (fever reduction), colorectal cancer protection, and suppressed inflammation. QUESTION 3: IBUPROFEN VS ACETAMINOPHEN Often patients ask the difference between ibuprofen and acetaminophen. Acetaminophen and ibuprofen share all of the following therapeutic effects except: a) Analgesia b) b) Antiinflammatory c) c) Antipyresis d) d) Pain relief B, anti-inflammatory. While acetaminophen and ibuprofen can provide pain relief (analgesia) and fever reduction (antipyresis), only ibuprofen can provide anti -inflammatory effects. So we have two basic branches, the drug that can’t affect inflammation and the one that can. QUESTION 4. THE CELECOXIB ADVANTAGE 4) What was thought of as a breakthrough was a selective cyclooxygenase inhibitor that might reduce GI distress from NSAID use. An arthritic patient with a history of GI distress and bleed might be a candidate for: a) Celecoxib b) Ibuprofen c) Naproxen ) Meloxicam A, celecoxib. Celecoxib was meant to protect against GI distress, but cardiac issues came up as patients took it reducing its utilization. Ibuprofen, naproxen, and meloxicam would likely eventually cause GI distress. QUESTION 5. THE DAILY ASPIRIN ISSUE In pharmacology, the best practice in using a medication can change even with the most common medicines. What concern about daily aspirin led to a change in the way prescribers look at it for protecting against cardiac events? a) Bleed risk that can outweigh protective benefit b) No longer suppresses platelet aggregation c) No longer protects against MI d) No longer protects against stroke A, Bleed risk that can outweigh protective benefit. While aspirin still suppresses platelet aggregation and can work to prevent MI and stroke in patients, the bleed risk is a concern. The new guidelines don’t apply to those who had a stroke/heart attack, underwent bypass surgery or had a stend procedure. These new guidelines apply to otherwise healthy adults and elderly with a high internal bleed risk.The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller americannurse. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for CA$14.67. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
73314 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now