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Exam (elaborations)

HEMA mockboard reviewer 6.

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HEMA mockboard reviewer 6
After a molecule of hemoglobin gains the first two oxygen molecules, the molecule
expels 2,3-DPG -
has decreased oxygen affinity
becomes saturated with oxygen
adds a molecule of oxygen to an alpha chain - ANS-expels 2,3-DPG -

An adult patient has a reticulocyte count of 4.8% and a Hct of 30%. This results indicate
adequate bone marrow response
inadequate bone marrow
response
within normal range
cannot be determined - ANS-inadequate bone marrow

As most blood cell lines mature, which of the following is characteristic?
Cell diameter increases
Nucleus to cytoplasm ratio (N:C) decreases
Nuclear chromatin becomes less condensed
Basophilia of the cytoplasm increases - ANS-Nucleus to cytoplasm ratio (N:C)
decreases

Because of the presence of abnormal hemoglobin that is not quantified correctly by a
multi-channel instrument, which of the following other results must be calculated by
hand?
MCV and RDW
MCH and RDW
MCV and MCH
MCH and MCHC - ANS-MCH and MCHC

Because the serum iron (SI) represents the number of transferrin sites bound with iron
and the TIBC represents the total number of transferrin sites for iron-binding, the degree
to which the available sites are occupied by iron can be calculated. The percent of
transferrin saturated with iron is calculated as:
TBIC/SI x 100%
TBIC x SI / 100%
SI/TIBC x 100%
TBIC + SI x 100% - ANS-SI/TIBC x 100%

, If normal adult (A1) and fetal hemoglobin F are compared, fetal hemoglobin has _____
affinity for oxygen.
less
the same
a greater - ANS-a greater

In a Wright-stained peripheral blood fi lm, the reticulocyte
will have a blue appearance. This is referred to as
megaloblastic maturation
bluemia
Polychromatophilia
Erythroblastosis - ANS-Polychromatophilia

In adults, hematopoietic tissue is located in the bone marrow, lymph nodes, spleen,
liver, and thymus. The bone marrow contains developing cells except
Macrophages
erythroid
myeloid
megakaryocytic and lymphoid cells - ANS-Macrophages

Marked red blood cell fragments will cause an abnormal histogram and/or scatterplots
on automated hematology analyzers for which of the following parameters?
White blood cells and red blood cells
Red blood cells and platelets
White blood cells and platelets
White blood cells, red blood cells, and platelets - ANS-Red blood cells and platelets

Megakaryopoiesis begins in what period:
mesoblastic period
hepatic period
myeloid period
none of these choices
none of these choices - ANS-hepatic period

One of the critical steps, when lead interferes with porphyrin synthesis, is converting
aminolevulinic acid (ALA) to porphobilinogen (PBG) by ______ also called PBG
synthase.
iron
protoporphyrin in the mitochondria
ALA dehydratase

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