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Test Bank for Understanding Pharmacology Essentials for Medication Safety, 3rd Edition by Workman-LaCharity, 9780323793506, Covering Chapters 1-29 | Includes Rationales

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Test Bank for Understanding Pharmacology Essentials for Medication Safety, 3rd Edition by Workman-LaCharity, 9780323793506, Covering Chapters 1-29 | Includes Rationales

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Contents
• 儒家伦理在商业和社会伦理中的应用
Chapter 。 Pages
(1) GENERAL PRINCIPLES OF PHARMACOLOGY ............................................................................................... 5
结论 ........................................................................................................................................ 5
PART I PHARMACOKINETICS
儒家思想持续是中国文化认同和社会组织的
PART II PHARMACODYNAMICS .................................................................................................................................... 8
(2) 基石。它在家庭动态、教育、政治治理和伦
AGENTS, CONTROLLING THE FUNCTIONS OF THE PERIPHERAL NERVOUS SYSTEM ................. 12
理道德方面的持久影响彰显了其在理解中国
PART I LOCAL ANESTHETICS ................................................................................................................................................................................ 12
文明中的重要性。随着中国应对现代挑战，
PART II CHOLINOMIMETIC DRUGS ...................................................................................................................................................................... 16
儒家思想的原则仍然具有重要意义，不仅塑
PART III CHOLINORECEPTOR BLOCKING DRUGS............................................................................................................................................. 19
PART IV ADRENORECEPTOR ACTIVATING DRUGS.......................................................................................................................................... 24
PART V ADRENORECEPTOR造个体行为，也影响国家政策的制定。
ANTAGONIST DRUGS .......................................................................................................................................... 29

(3) AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM ........................ 34
这篇文章通过结构化的方法全面探讨了该主
PART I HYPNOTIC DRUGS ...................................................................................................................................................................................... 34
题。每个部分可以通过历史例子、儒家经典
PART II ANTISEIZURE DRUGS ............................................................................................................................................................................... 38
引文以及现代解读进行扩展。如果您希望探
PART III ANTIPARKINSONIAN AGENTS .............................................................................................................................................................. 41
PART IV ETHYL ALCOHOL讨中国文化的其他方面或对主题进行任何修
.................................................................................................................................................................................... 44
PART V NARCOTIC ANALGESICS ......................................................................................................................................................................... 46
改，请告诉我！
PART VI NON-NARCOTIC ANALGESICS ............................................................................................................................................................. 49
PART VII ANTIPSYCHOTIC AGENTS .................................................................................................................................................................... 51
PART VIII ANTIDEPRESSANT•AGENTS 儒家伦理在商业和社会伦理中的应用
............................................................................................................................................................... 54
PART IX ANXIOLYTIC AGENTS ............................................................................................................................................................................ 57
。
PART X CNS STIMULANTS .................................................................................................................................................................................... 60
PART XI DRUGS OF ABUSE.................................................................................................................................................................................... 63
结论 ...................................................................................................................................................................... 65
PART XII GENERAL ANESTHETICS
(4) ORGANOTROPIC儒家思想持续是中国文化认同和社会组织的
AGENTS .................................................................................................................................. 68
PART I DRUGS ACTING ON 基石。它在家庭动态、教育、政治治理和伦
RESPIRATORY SYSTEM ......................................................................................................................................... 68
PART II DRUGS USED IN GASTROINTESTINAL 理道德方面的持久影响彰显了其在理解中国 DISEASES ............................................................................................................................... 70
PART III DRUGS ACTING ON HEMATOPOIETIC SYSTEM ................................................................................................................................. 73
文明中的重要性。随着中国应对现代挑战，
PART IV DRUGS USED IN DISORDERS OF COAGULATION.............................................................................................................................. 74
PART V DRUGS USED FOR 儒家思想的原则仍然具有重要意义，不仅塑
TREATMENT OF HEART FAILURE ........................................................................................................................ 76
PART VI ANTIARRHYTHMIC 造个体行为，也影响国家政策的制定。
AGENTS ................................................................................................................................................................. 78
PART VII DRUGS FOR ANGINA PECTORIS TREATMENT ................................................................................................................................ 80
PART VIII ANTIHYPERTENSIVE DRUGS ............................................................................................................................................................. 83
PART IX HYPERTENSIVE这篇文章通过结构化的方法全面探讨了该主 (ANTI-HYPOTENSIVE) DRUGS. DRUGS INFLUENCING CEREBRAL BLOOD FLOW. ANTI-MIGRAINE
题。每个部分可以通过历史例子、儒家经典
AGENTS ......................................................................................................................................................................................................................... 85
(5) 引文以及现代解读进行扩展。如果您希望探
METABOLIC PROFILE DRUGS .......................................................................................................................... 88
PART I HYPOTHALAMIC 讨中国文化的其他方面或对主题进行任何修
& PITUITARY HORMONES, THYROID & ANTITHYROID DRUGS .................................................................. 88
改，请告诉我！
PART II PANCREATIC HORMONES & ANTIDIABETIC DRUGS ...................................................................................................................... 91
PART III THE GONADAL HORMONES & INHIBITORS ..................................................................................................................................... 93
PART IV GLUCOCORTICOID, STEROIDAL & NONSTEROIDAL ANTI-INFLAMMATORY DRUGS.......................................................... 95
儒家伦理在商业和社会伦理中的应用
PART V IMMUNOTROPIC & A•NTIALLERGIC AGENTS .................................................................................................................................... 98
PART VI VITAMINS, VITAMIN-LIKE
。 COMPOUNDS, ANTIVITAMINS, ENZYMES & ANTIENZYMES ................................................. 104
PART VII ANTIHYPERLIPIDEMIC DRUGS & DRUGS USED IN THE TREATMENT OF GOUT ............................................................... 110
PART VIII AGENTS THAT AFFECT BONE MINERAL HOMEOSTASIS ....................................................................................................... 114
结论 , MINERALOCORTICOID ANTAGONISTS, DIURETICS, PLASMA EXPANDERS ............................. 120
PART IX MINERALOCORTICOID
(6) 儒家思想持续是中国文化认同和社会组织的
CHEMOTHERAPEUTIC DRUGS ....................................................................................................................... 124
基石。它在家庭动态、教育、政治治理和伦
PART I ANTIBIOTICS .................................................................................................................................................... 124
理道德方面的持久影响彰显了其在理解中国
PART II SYNTHETIC ANTIBACTERIAL DRUGS ....................................................................................................... 129
文明中的重要性。随着中国应对现代挑战，
PART III ANTIPROTOZOAL AND ANTHELMINTIC DRUGS ................................................................................... 132
PART IV ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER .................................................. 135
儒家思想的原则仍然具有重要意义，不仅塑
造个体行为，也影响国家政策的制定。

这篇文章通过结构化的方法全面探讨了该主
题。每个部分可以通过历史例子、儒家经典
引文以及现代解读进行扩展。如果您希望探
讨中国文化的其他方面或对主题进行任何修
改，请告诉我！
Multiple choice questions
Multiple choice questions

, 5
儒家伦理在商业和社会伦理中的应用
•
(1) 。
GENERAL PRINCIPLES OF PHARMACOLOGY

PART I PHARMACOKINETICS
结论
01. Pharmacokinetics is:
儒家思想持续是中国文化认同和社会组织的
a) The study of biological and therapeutic effects of drugs
基石。它在家庭动态、教育、政治治理和伦
b) The study of absorption, distribution, metabolism and excretion of drugs
c) The study of mechanisms of drug action
d) The study of methods理道德方面的持久影响彰显了其在理解中国
of new drug development
文明中的重要性。随着中国应对现代挑战，
02. What does “pharmacokinetics” include?
a) Complications of drug therapy
儒家思想的原则仍然具有重要意义，不仅塑
b) Drug biotransformation in the organism
c) Influence of drugs on造个体行为，也影响国家政策的制定。
metabolism processes
d) Influence of drugs on genes
02. What does “pharmacokinetics” include?
这篇文章通过结构化的方法全面探讨了该主
a) Pharmacological effects of drugs
题。每个部分可以通过历史例子、儒家经典
b) Unwanted effects of drugs
c) Chemical structure of a medicinal agent
引文以及现代解读进行扩展。如果您希望探
d) Distribution of drugs in the organism
讨中国文化的其他方面或对主题进行任何修
03. What does “pharmacokinetics” include?
改，请告诉我！
a) Localization of drug action
b) Mechanisms of drug action
c) Excretion of substances
d) Interaction of substances• 儒家伦理在商业和社会伦理中的应用
04. The main mechanism of most drugs absorption in GI tract is:
。 diffusion)
a) Active transport (carrier-mediated
b) Filtration (aqueous diffusion)
c) Endocytosis and exocytosis
结论
d) Passive diffusion (lipid diffusion)
儒家思想持续是中国文化认同和社会组织的
05. What kind of substances can’t permeate membranes by passive diffusion?
a) Lipid-soluble 基石。它在家庭动态、教育、政治治理和伦
b) Non-ionized substances
理道德方面的持久影响彰显了其在理解中国
c) Hydrophobic substances
文明中的重要性。随着中国应对现代挑战，
d) Hydrophilic substances
06. A hydrophilic medicinal儒家思想的原则仍然具有重要意义，不仅塑
agent has the following property:
a) Low ability to penetrate through the cell membrane lipids
造个体行为，也影响国家政策的制定。
b) Penetrate through membranes by means of endocytosis
c) Easy permeation through the blood-brain barrier
d) High reabsorption in renal tubules
这篇文章通过结构化的方法全面探讨了该主
07. What is implied by «active transport»?
题。每个部分可以通过历史例子、儒家经典
a) Transport of drugs trough a membrane by means of diffusion
b) Transport without energy consumption
引文以及现代解读进行扩展。如果您希望探
c) Engulf of drug by a cell membrane with a new vesicle formation
讨中国文化的其他方面或对主题进行任何修
d) Transport against concentration gradient
改，请告诉我！
08. What does the term “bioavailability” mean?
a) Plasma protein binding degree of substance
b) Permeability through the brain-blood barrier
c) Fraction of an uncharged 儒家伦理在商业和社会伦理中的应用
• drug reaching the systemic circulation following any route administration
d) Amount of a substance in urine relative to the initial doze
。 are:
09. The reasons determing bioavailability
a) Rheological parameters of blood
b) Amount of a substance 结论 obtained orally and quantity of intakes
c) Extent of absorption and hepatic first-pass effect
儒家思想持续是中国文化认同和社会组织的
d) Glomerular filtration rate
10. Pick out the appropriate基石。它在家庭动态、教育、政治治理和伦
alimentary route of administration when passage of drugs through liver is minimized:
a) Oral
b) Transdermal 理道德方面的持久影响彰显了其在理解中国
c) Rectal 文明中的重要性。随着中国应对现代挑战，
d) Intraduodenal
儒家思想的原则仍然具有重要意义，不仅塑
11. Which route of drug administration is most likely to lead to the first-pass effect?
a) Sublingual 造个体行为，也影响国家政策的制定。

这篇文章通过结构化的方法全面探讨了该主
题。每个部分可以通过历史例子、儒家经典
引文以及现代解读进行扩展。如果您希望探
讨中国文化的其他方面或对主题进行任何修
改，请告诉我！
Multiple choice questions
Multiple choice questions

, 6
• 儒家伦理在商业和社会伦理中的应用
b) Oral 。
c) Intravenous
d) Intramuscular
12. What is characteristic of结论
the oral route?
a) Fast onset of effect 儒家思想持续是中国文化认同和社会组织的
b) Absorption depends on GI tract secretion and motor function
基石。它在家庭动态、教育、政治治理和伦
c) A drug reaches the blood passing the liver
理道德方面的持久影响彰显了其在理解中国
d) The sterilization of medicinal forms is obligatory
13. Tick the feature of the sublingual route:
a) Pretty fast absorption
文明中的重要性。随着中国应对现代挑战，
b) A drug is exposed to儒家思想的原则仍然具有重要意义，不仅塑
gastric secretion
c) A drug is exposed more prominent liver metabolism
造个体行为，也影响国家政策的制定。
d) A drug can be administrated in a variety of doses
14. Pick out the parenteral route of medicinal agent administration:
a) Rectal 这篇文章通过结构化的方法全面探讨了该主
b) Oral
c) Sublingual
题。每个部分可以通过历史例子、儒家经典
d) Inhalation 引文以及现代解读进行扩展。如果您希望探
讨中国文化的其他方面或对主题进行任何修
15. Parenteral administration:
a) Cannot be used with unconsciousness patients
b) Generally results in a改，请告诉我！
less accurate dosage than oral administration
c) Usually produces a more rapid response than oral administration
d) Is too slow for emergency use
• 儒家伦理在商业和社会伦理中的应用
16. What is characteristic of the intramuscular route of drug administration?
。
a) Only water solutions can be injected
b) Oily solutions can be injected
c) Opportunity of hypertonic solution injections
d) The action develops 结论slower, than at oral administration
儒家思想持续是中国文化认同和社会组织的
17. Intravenous injections are more suitable for oily solutions:
a) True
b) False 基石。它在家庭动态、教育、政治治理和伦
理道德方面的持久影响彰显了其在理解中国
18. Correct statements listing characteristics of a particular route of drug administration include all of the following EXCEPT:
文明中的重要性。随着中国应对现代挑战，
a) Intravenous administration provides a rapid response
b) Intramuscular administration requires a sterile technique
c) Inhalation provides儒家思想的原则仍然具有重要意义，不仅塑
slow access to the general circulation
造个体行为，也影响国家政策的制定。
d) Subcutaneous administration may cause local irritation
19. Most of drugs are distributed homogeneously.
a) True
b) False 这篇文章通过结构化的方法全面探讨了该主
题。每个部分可以通过历史例子、儒家经典
20. Biological barriers include all except:
a) Renal tubules
b) Cell membranes
引文以及现代解读进行扩展。如果您希望探
c) Capillary walls 讨中国文化的其他方面或对主题进行任何修
d) Placenta
改，请告诉我！
21. What is the reason of complicated penetration of some drugs through brain-blood barrier?
a) High lipid solubility of a drug
b) Meningitis • 儒家伦理在商业和社会伦理中的应用
c) Absence of pores in the brain capillary endothelium
d) High endocytosis degree in a brain。 capillary
22. The volume of distribution (Vd) relates:
a) Single to a daily dose of an administrated drug
结论
b) An administrated dose to a body weight
儒家思想持续是中国文化认同和社会组织的
c) An uncharged drug reaching the systemic circulation
d) The amount of a drug in the body to the concentration of a drug in plasma
基石。它在家庭动态、教育、政治治理和伦
23. For the calculation of the volume of distribution (Vd) one must take into account:
a) Concentration of a 理道德方面的持久影响彰显了其在理解中国
substance in plasma
文明中的重要性。随着中国应对现代挑战，
b) Concentration of substance in urine
c) Therapeutical width of drug action
d) A daily dose of drug 儒家思想的原则仍然具有重要意义，不仅塑
造个体行为，也影响国家政策的制定。
24. A small amount of the volume of distribution is common for lipophylic substances easy penetrating through barriers and
widely distributing in plasma, interstitial and cell fluids:

这篇文章通过结构化的方法全面探讨了该主
题。每个部分可以通过历史例子、儒家经典
引文以及现代解读进行扩展。如果您希望探
讨中国文化的其他方面或对主题进行任何修
改，请告诉我！
Multiple choice questions
Multiple choice questions

, • 儒家伦理在商业和社会伦理中的应用 7
。
a) True
b) False
结论 includes the following:
25. The term “biotransformation”
儒家思想持续是中国文化认同和社会组织的
a) Accumulation of substances in a fat tissue
b) Binding of substances with plasma proteins
基石。它在家庭动态、教育、政治治理和伦
c) Accumulation of substances in a tissue
理道德方面的持久影响彰显了其在理解中国
d) Process of physicochemical and biochemical alteration of a drug in the body
26. Biotransformation of the drugs is to render them:
文明中的重要性。随着中国应对现代挑战，
a) Less ionized
儒家思想的原则仍然具有重要意义，不仅塑
b) More pharmacologically active
c) More lipid soluble 造个体行为，也影响国家政策的制定。
d) Less lipid soluble
27. Tick the drug type for which microsomal oxidation is the most prominent:
a) Lipid soluble 这篇文章通过结构化的方法全面探讨了该主
b) Water soluble 题。每个部分可以通过历史例子、儒家经典
c) Low molecular weight
d) High molecular weight引文以及现代解读进行扩展。如果您希望探
讨中国文化的其他方面或对主题进行任何修
28. Pick out the right statement:
a) Microsomal oxidation always results in inactivation of a compound
b) Microsomal oxidation改，请告诉我！
results in a decrease of compound toxicity
c) Microsomal oxidation results in an increase of ionization and water solubility of a drug
d) Microsomal oxidation results in an increase of lipid solubility of a drug thus its excretion from the organism is facilitated
• 儒家伦理在商业和社会伦理中的应用
29. Stimulation of liver microsomal enzymes can:
a) Require the dose increase of 。some drugs
b) Require the dose decrease of some drugs
c) Prolong the duration of the action of a drug
d) Intensify the unwanted结论reaction of a drug
30. Metabolic transformation 儒家思想持续是中国文化认同和社会组织的
(phase 1) is:
a) Acetylation and methylation of substances
基石。它在家庭动态、教育、政治治理和伦
b) Transformation of substances due to oxidation, reduction or hydrolysis
c) Glucuronide formation 理道德方面的持久影响彰显了其在理解中国
d) Binding to plasma proteins
文明中的重要性。随着中国应对现代挑战，
31. Biotransformation of a medicinal substance results in:
儒家思想的原则仍然具有重要意义，不仅塑
a) Faster urinary excretion
造个体行为，也影响国家政策的制定。
b) Slower urinary excretion
c) Easier distribution in organism
d) Higher binding to membranes
32. Conjugation is: 这篇文章通过结构化的方法全面探讨了该主
题。每个部分可以通过历史例子、儒家经典
a) Process of drug reduction by special enzymes
b) Process of drug oxidation by special oxidases
c) Coupling of a drug 引文以及现代解读进行扩展。如果您希望探
with an endogenous substrate
d) Solubilization in lipids讨中国文化的其他方面或对主题进行任何修
33. Which of the following processes proceeds in the second phase of biotransformation?
改，请告诉我！
a) Acetylation
b) Reduction
c) Oxidation
d) Hydrolysis • 儒家伦理在商业和社会伦理中的应用
。following EXCEPT:
34. Conjugation of a drug includes the
a) Glucoronidation
b) Sulfate formation
c) Hydrolysis 结论
d) Methylation 儒家思想持续是中国文化认同和社会组织的
35. Metabolic transformation and conjugation usually results in an increase of a substance biological activity:
a) True
基石。它在家庭动态、教育、政治治理和伦
b) False 理道德方面的持久影响彰显了其在理解中国
文明中的重要性。随着中国应对现代挑战，
36. In case of liver disorders accompanied by a decline in microsomal enzyme activity the duration of action of some drugs
is:
a) Decreased 儒家思想的原则仍然具有重要意义，不仅塑
b) Enlarged 造个体行为，也影响国家政策的制定。
c) Remained unchanged
d) Changed insignificantly
这篇文章通过结构化的方法全面探讨了该主
题。每个部分可以通过历史例子、儒家经典
引文以及现代解读进行扩展。如果您希望探
讨中国文化的其他方面或对主题进行任何修
改，请告诉我！
Multiple choice questions
Multiple choice questions

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