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AAB MT Hematology Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution CA$11.53   Add to cart

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AAB MT Hematology Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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AAB MT Hematology Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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  • June 26, 2024
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  • 2023/2024
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AAB MT Hematology
What is hemoglobin composed of? - ANS-4 heme, 4 iron, 4 globins

What disorder does a defect in heme synthesis lead to? - ANS-Porphyria

Porphyria - ANS-Deficiency in the enzymes of the porphyrin pathway leads to
insufficient production of heme. The principal problem in these deficiencies is the
accumulation of porphyrins, the heme precursors, which are toxic to tissue in high
concentrations.

What is methemoglobin? - ANS-Methemoglobin is a form of hemoglobin that contains
ferric [Fe3+] iron and has a decreased ability to bind oxygen. However, the ferric iron
has an increased affinity for bound oxygen. When methemoglobin concentration is
elevated in red blood cells, tissue hypoxia can occur.

What is the function of the enzyme methemoglobin-cytochrome C reductase in a red
blood cell? - ANS-To keep iron in the ferrous state

What product is formed when ferrous iron of hemoglobin is oxidized to the ferric state? -
ANS-Methemoglobin

What is carboxyhemoglobin? - ANS-A stable complex of carbon monoxide and
hemoglobin that forms in RBCs when carbon monoxide is inhaled or produced in normal
metabolism. Large quantities of it hinder delivery of O2 to the body. Tobacco smoking
(through carbon monoxide inhalation) raises the blood levels of COHb by a factor of
several times from its normal concentrations.

Which hemoglobin has a 200 times greater binding capacity for the hemoglobin
molecule than oxygen? - ANS-Carboxyhemoglobin

Which hemoglobin derivative causes irreversible changes in RBCs? -
ANS-Sulfhemoglobin -- makes blood incapable of carrying oxygen.

Which of the following hemoglobins is NOT normally present in a normal adult? -
ANS-Hb-S

Which embryonic hemoglobin is normally found in newborns? - ANS-Hb-F

What is the most abundant hemoglobin in a newborn? - ANS-Hb-F

,What is the molecular structure of Hemoglobin S? - ANS-Valine replaces glutamic acid
in the 6th position of the beta chain

Which of the following hemoglobins is insoluble under lowered oxygen tension? -
ANS-Hb-S

What laboratory test is used to confirm the specific diagnosis of sickle cell anemia? -
ANS-Hemoglobin electrophoresis

In the solubility test for hemoglobin S, what is the reagent responsible for the reduction
of the hemoglobin molecule? - ANS-Sodium dithionite

In hemoglobin C, what replaces glutamic acid? - ANS-Lysine

Which red blood cell inclusion is characteristic of hemoglobin C disease? -
ANS-Rod-shaped crystals

What is hemoglobin F composed of? - ANS-2 alpha and 2 gamma chains

Which hemoglobin is resistant to alkali denaturation? - ANS-Hb-F

Which hemoglobins are differentiated by the Kleihauer-Betke technique? - ANS-Hb-A1
from Hb-F

What is the order of migration of hemoglobins, from fastest to slowest, on cellulose
acetate at pH 8.4? - ANS-A1, F, S, C

Why is citrate agar used when abnormal hemoglobins are identified on cellulose acetate
at pH 8.6? - ANS-It separates hemoglobin S from hemoglobin D

The cyanmethemoglobin method measures all hemoglobin pigments EXCEPT which
one? - ANS-Sulfhemoglobin

What is the diluent used in the cyanmethemoglobin method for the determination of
hemoglobin? - ANS-Drabkin's solution

What is the normal plasma hemoglobin concentration? - ANS-2-3 mg/dL

Which plasma protein binds free hemoglobin? - ANS-Haptoglobin

, Which one of the following statements concerning hemolytic anemia is false? -
ANS-The serum haptoglobin is increased

In this type of anemia RBCs are normocytic and normochromic. RBCs, hemoglobin, and
hematocrit are decreased and the indirect bilirubin is increased. - ANS-Hemolytic
anemia

Myoglobin can be separated from hemoglobin by saturating the specimen with which
one of the following reagents? - ANS-Ammonium sulfite

The hematocrit is also known as which one of the following terms? - ANS-Packed red
blood cell volume

The degree of packing of cells during centrifugation depends on all of the following
EXCEPT which one? - ANS-Bore size of the microhematocrit tube

The degree of packing of cells during centrifugation depends on all of the following: -
ANS-Speed of the centrifugation, radius of centrifugation, and time of centrifugation.

During examination of a spun hematocrit, in which layer are the white blood cells found?
- ANS-Buffy coat

When performing a microhematocrit, where should one read the percentage of packed
red blood cell column from a microhematocrit reading device? - ANS-Below the buffy
coat

An increase in the erythrocyte sedimentation rate can be the result of an increase in the
quantity of which of the following? - ANS-Fibrinogen

Which test is increased in acute infections? - ANS-Osmotic fragility

All of the following sources of error will falsely elevate the ESR EXCEPT which one? -
ANS-Polycythemia

All of the following sources of error will falsely elevate the ESR? - ANS-Tilted tube,
macrocytes, and vibrations from a nearby centrifuge.

What is the Westergren ESR reference range for males? - ANS-0-15 mm/hr

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