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Endometrial Hyperplasia and Carcinoma Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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Endometrial Hyperplasia and Carcinoma Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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  • June 26, 2024
  • 5
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers

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  • endometrial hyperplasia and carcinoma questions wi

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  • Men & Women's Health
  • Men & Women's Health
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Endometrial Hyperplasia and Carcinoma
What drives growth of endometrium? - ANS-Estrogen (proliferative phase)

What drives preparation of endometrium for implantation? - ANS-Progesterone
(secretory phase)

What is acute endometritis, and how does it present? - ANS-Bacterial infection of
endometrium 2/2 retained products of conception
Fever, abnormal uterine bleeding, & pelvic pain

What is chronic endometritis, and how does it present? - ANS-Chronic inflammation of
endometrium 2/2 retained products of conception, PID, IUD, & TB
Abnormal uterine bleeding, pelvic pain, & infertility

What are histologic features of chronic endometritis? - ANS-Plasma cells

What are endometrial polyps, and how do they present? - ANS-Hyperplastic protrusion
of endometrium
Abnormal uterine bleeding

What are causes of endometrial polyps? - ANS-Side effect of tamoxifen (anti-estrogen
in breast, pro-estrogen in endometrium)

What is endometriosis, and how does it present? - ANS-Endometrial glands & stroma
outside uterine endometrial lining
Dysmenorrhea & pelvic pain, may cause infertility

What are causes of endometriosis? - ANS-Retrograde menstruation theory = prevailing
theory
Metaplastic theory: endothelial metaplasia of mullerian duct
Lymphatic dissemination theory

What are the common sites of endometriosis? - ANS-Ovary = most common —>
chocolate cyst (gunpowder lesions if involving soft tissue)
Uterine myometrium = adenomyosis
Uterine ligaments —> pelvic pain
Pouch of Douglas —> pain w/ defecation
Bladder wall —> pain w/ urination

, Bowel serosa —> abdominal pain & adhesions
Fallopian tube mucosa —> scarring —> increased risk of infertility & ectopic pregnancy

What is adenomyosis? - ANS-Uterine thickening that occurs when endometrial tissue
moves into muscular walls of uterus (rather than just lining uterus) = endometriosis w/in
myometrium

What are complications of endometriosis? - ANS-Increased risk of carcinoma at site of
endometriosis, esp. ovary

What is endometrial hyperplasia, and how does it present? - ANS-Hyperplasia of
endometrial glands relative to stroma 2/2 unopposed estrogen
Postmenopausal uterine bleeding

What are histologic features of endometrial hyperplasia? - ANS-Based on architectural
growth & cellular atypia

What is the most important predictor for progression of hyperplasia to carcinoma? -
ANS-Cellular atypia

What are complications of endometrial hyperplasia? - ANS-Increased risk of
endometrial carcinoma

What is endometrial carcinoma, and how does it present? - ANS-Malignant proliferation
of endometrial glands
Postmenopausal or abnormal uterine bleeding —> endometrial stripe thickness > 5 mm
on transvaginal US

What are risk factors for endometrial carcinoma? - ANS-Unopposed estrogen
Tamoxifen
Late menopause
PCOS
Obesity
Granulosa cell tumor
Lynch syndrome

What are the pathways that lead to endometrial carcinoma? - ANS-Type I: unopposed
estrogen —> endometrial hyperplasia —> endometrial adenocarcinoma (in women age
50-60, heavier)

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