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ONS_ONCC Chemotherapy Immunotherapy Certificate questions and answers
ONS_ONCC Chemotherapy Immunotherapy Certificate questions and answers
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ONS/ONCC ChemotherapyImmunotherapy Certificate
-Exceptions to this are those that are (Resting in G0 phase) - correct answer--Exceptions to
this are those that are metabollically active, such as
-granulocytes
-and the epithelium of the GI tract
1. Elimination of the Hazard: - correct answer--highest level of protection from a hazardous
exposure
-substitute a less toxic substance for the hazardous material
-not feasible with drug therapy
1. Phagocytes
2. Natural Killer Cells
3. Granulocytes
4. Macrophages - correct answer-1.Cells that engulf and destroy invader
2. Cells that sense receptors on self and non-self to determine if they should kill or not
3. Type of WBC that have granules (Neutrophils
Eosinophils - parasites
Basophils - release histamine to stimulate immune response)
4. Large phagocytic cells stimulated by infection
2. Engineering Controls - correct answer--second highest level of protection
-use of machines or equipment that isolate or contain the hazard to reduce worker exposure
-Examples: biosafety cabinets and closed-system drug-transfer devices
3. Administrative Controls - correct answer--third level of protection
-safe handling policies
-procedures
-work practices
-education and training of those responsible for HD handling
,4. PPE - correct answer--lowest form of protection
-consisting of garments that provide barriers to protect workers from HDs
-places the primary responsibility for protection on the worker
Absolute Neutrophil Count - correct answer-- (%segs + %bands) x (WBC) / 100
Active Immunotherapy - correct answer--capitalize on the immune system's ability to
remember a foreign invade
-mount an immune response against the tumor and hopefully remember the cancer cells
long after treatment has stopped
-includes cancer vaccines
Adaptive Immunity - correct answer--Stimulated if innate immunity is insufficient
-leads to immune system memory
-Humoral immunity
-Cell-mediated immunity
-Regulatory T-cells
Adjuvant therapy - correct answer--additonal cancer treatment given after the primary
treatment to lower the risk that the cancer can recur
-Examples: chemo, radiation therapy, hormone therapy, targeted therapy, or biologic therapy
Alkylating Agent Subgroups - correct answer--Nitrogen mustards
(cyclophosphamide{Cytoxin}, ifosfamide{Ifex}, bendamustine{Treanda})
-Platinum-based (cisplatin{Planitol}, carboplatin{Paraplatin}): do not possess an alkyl group
-nitrosoureas
Alkylating Agents - correct answer--function by causing a break in the DNA helix strand,
causing interference with DNA replication, which results in cell death
B-Cell - correct answer--each one is programmed to make one specific antibody
-Can recognize antigens whether they are freely circulating in the blood or attached to
surface of a microbe
, -When dividing, can become plasma cells which will then begin secreting antibodies that are
unique to that antigen
BCR/ABL - correct answer--fusion protein tyrosine kinase formed with a gene translocation
occurs between gene 9 and 22
-gene abnormality called the Philadelphia chromosome seen in CML and ALL
Benign Tumors - correct answer--encapsulated and grow in an orderly manner with smooth
edges
-Do not invade neighboring tissue
-DO not metastasize to distant sites
-the cells well differentiated in that they look like the parent cell
Can I be intimate with my partner during treatment? - correct answer--you should definiely
check with your HCP first to be sure
-traces of chemo may be present in vaginal fluid for up to 48 hours after treatment
-use of a barrier is recommended for this reason for at least the first 48 hours
Carboplatin (Paraplatin) - correct answer--Alkylazing agent
-possibility for a hypersensitivity reaction which is rash, urticaria, erythema, pruritis, rarely
bronchospasm and hypotensision
-notify RN if itching, scratchy throat, difficulty breathing, rash
-Blood count, particularly platelets, monitored because thrombocytopenia is a dose-limiting
toxicity
-Oral dosage: 1-5mg/kg/day
Cell cycle video and image - correct
answer-http://highered.mheducation.com/sites/0072495855/student_view0/chapter2/animati
on__how_the_cell_cycle_works.html
Cell Cycling Time - correct answer-Amount of time from mitosis to mitosis
Cell-Mediated Immunity - correct answer-Depends upon cytotoxic T cells and helper T cells
and their cyokinds
-more effective against antigens within cells
Cells of the Immune System - correct answer-
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