Exam (elaborations)
Clozaril (clozapine)
- Institution
- Act 1-3 The Tragedy Of Julius Caesar
Clozaril (clozapine)
[Show more]
Seller
Follow
Content preview
Clozaril (clozapine)Dose range - ANS-PO: initial dose: 12.5 mg 1-2 times a day
Target dose: 150-500 mg/day
Do not exceed 900 mg/day
Drug classification - ANS--- atypical antipsychotic
Evaluation of medication effectiveness - ANS-- decreased positive symptoms (delusions,
hallucinations) of schizophrenia
- decreased negative symptoms (social withdrawal,
flat, blunted affect) of schizophrenia
Medication/Food interactions - ANS-- increased anticholinergic effect of other drugs
- oral contraceptives and caffeine may increase effect
- increased CNS depression with alcohol, anti-
depressants, antihistamines, opioids, sedative
hypnotics
- using with Lithium increases adverse CNS reactions
including seizures
- no St. John's Wort
Nursing administration (concerns) - ANS-- monitor WBCs and ANC (absolute neutrophil count)
- assess fasting blood glucose
- lowers seizure threshold
- assess respiratory status
- need baseline WBC, and then every 1 week during
treatment and for 4 weeks after
- agranulocytosis can occur 18-24 weeks after initiation
of therapy
Nursing interventions/Client education - ANS-- inform patient /monitor for extrapyramidal
symptoms
- cigarette smoking may decrease clozapine levels
- avoid alcohol and CNS depressants
- notify MD if unexplained palpitations, tachypnea,
chest pain, sore throat, flu-like symptoms
- Notify MD if pregnant or breastfeeding
Pharmacological action - ANS-- binds to dopamine receptors in the CNS
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller lydiaomutho. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for CA$11.54. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
80467 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now