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NUR 2060 Cancer Drugs (2) CA$11.68
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NUR 2060 Cancer Drugs (2)

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NUR 2060 Cancer Drugs (2)

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  • July 22, 2024
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  • 2023/2024
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NUR 2060 Cancer Drugs
what are ADRs of etoposide (VePesid, VP-16)? - ANS-orthostatic hypotension (espically w/ fast
push)

alopecia, myelosuppression
hypersensitivity

What are the taxane drugs? What are they used for? ADRs? - ANS---paclitaxel (Taxol)'
--docetaxal (Taxotere)
--used for lung, ovarian, gastric, breast--infuse SLOWLY--use H1 & H2 blockers BEFORE
paclitaxel (Taxol) dose--use dexamethasone BEFORE docetaxal (Taxotere)

What is allopurinol (Zyloprim) used to treat? - ANS---its an anti-uric drug that you start BEFORE
chemo to prevent tumor lysis syndrome (TLS)

What is anastrozole (Arimidex) used to treat? ADRs? - ANS---inhibits enzyme necessary for
adrenals to synthesize estrogen
--ADRs: osteoporosis, hot flashes, but NO risk of DVT/PE

What is asparaginase (Elspar) used for? Action? ADRs? - ANS---used to treat acute leukemias
--action is to deprive cells of essential amino acids needed to synthesis proteins
--ADRs: coagulation difficulties, injury to liver, pancreas & kidneys, CNS depression,
hypersensitivity, anaphylaxis

What is bleomycin (Blenoxane) used for? ADRs? - ANS---anti-tumor antibiotic
--for tx of: lymphoma, squamous cell carcinoma, testicular cancer--ADRs: pulmonary fibrosis,
pneumonitis, anaphylaxis

What is carmustine (BCNU) used to treat? What else (other than cancer) can the drug be used
to treat/help? - ANS---used to treat: primary & metastatic CA's of CNS, Hodgkin &
non-Hodgkin's myeloma, liver, colon, rectum and stomach CA
--used in high dose regimes for transplants

What is cisplatin (Platinol) used to treat? ADRs? - ANS---used in combination to treat: ovarian &
cervical CA, testicular CA, lung CA, colon CA
--ADRs: myleosuppression, N/V, neuropathy, hypersensitivity, renal toxic

What is cyclophosphamide (Cytoxan) used to treat? Action? ADRs? Toxicity? - ANS---cytotoxic
agent
--action is to alter DNA

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