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NUR 2060 Pain Drugs (1)

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NUR 2060 Pain Drugs (1)

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  • July 22, 2024
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  • 2023/2024
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NUR 2060 Pain Drugs
acetaminophen (Tylenol)* - ANS---analgesic, antipyretic
--max dose = 4000 mg/day
--NOT an NSAID/anti-inflammatory
--hepatotoxicity risk w/ high doses
--antidote = acetylcysteine (Acetadote)

aspirin (acetylsalicylic acid, ASA)* - ANS---analgesic, antipyretic, anti-inflammatory, suppresses
platelet aggregation
--uses: RA, pain, stroke prevention, MI, TIAs, angina, dysmenorrhea
--ADRs: GI upset, bleeding
--salicylism = tinnitus, sweating, HA, dizziness
--interactions = highly protein bound

ibuprofen (Advil, Motrin, Caldolor, etc.)* - ANS---NSAID (inhib COX1 & COX2)
--Caldolor = IV form
--analgesic, antipyretic, anti-inflammatory
--uses: RA, OA, pain, fever, bursitis, tendonitis
--ADRs: GI upset, ulceration, bleeding, renal failure, anaphylaxis, HTN

naproxen (Anaprox, Naprosyn, Aleve)* - ANS---NSAID (inhib COX1 & COX2)
--analgesic, antipyretic, anti-inflammatory
--uses: RA, OA, pain, fever, bursitis, tendonitis
--ADRs: GI upset, ulceration, bleeding, renal failure, anaphylaxis, HTN

gabapentin (Neurontin)* - ANS---neuropathic pain tx
--common analgesic adjunct

pregabalin (Lyrica)* - ANS---neuropathic pain tx
--fibromyalgia tx
--common analgesic adjunct

hydrocodone/acetaminophen (Norco)* - ANS---binds to Mu opioid receptors
--dose limited by acetaminophen (opioids don't have ceiling effect)
--tx moderate to severe pain (4,5,6 pain lvl)

tramadol (Ultram)* - ANS---binds to mu opioid receptors
--inhibits uptake of SE
and NE in CNS
--equianalgesic to T3s (not strong)
--max dose = 400 mg/day

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