BRM-s (Biological Response Modifiers) used for RA (1)

BRM's (Biological Response Modifiers) used for RA
serious infection
TB
MS - ANS-Contraindicated in which patients?

Crowds
Live vaccines
Ppl with infections - ANS-What patients should avoid when taking BRMs?

Etanercept (Enbrel)
Infliximab
Adalimunab
Anakinra - ANS-After administration, monitor site for reaction

Infliximab - ANS-Only BRM that shouldn't be refrigerated

Tocilizumab - ANS-May cause decrease in WBCs, platelets and liver dysfunction

Anakinra - ANS-May cause severe decrease in WBC count

Infliximab - ANS-Patient is to report chest pain or difficulty breathing during infusion, and monitor
bp

Abatacept - ANS-Patient is to report cough, dizziness and sore throat; not to receive love
vaccines while taking this drug

Golimumab - ANS-Patient is to report s/s of infection, including fever and malaise; should avoid
live vaccines while taking this drug

Rituximab - ANS-Drug has a BLACK BOX WARNING about serious infections

Rituximab - ANS-Observe for infusion reaction as for entanercept

Abatacept - ANS-Monitor for dyspnea, wheezing, Flushing, and itching

Golimumab - ANS-Adverse effects include HTN, GI distress and infection

Anakinra - ANS-Patient is to report respiratory symptoms such as cough and fever;
malignancies can result