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NUR 219 - Patho Exam 1 Review Questions and Correct Answers
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Pharmacology study of drugs and interactions with living systems Pharamacotherapeutics provide maximum benefits with minimum harm -medical use of drugs Pharmacology clinical study of drugs on people What is a drug? any chemical that can affect living process -all chemicals are drugs What is an ...

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  • August 3, 2024
  • 8
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • nur 219 patho exam 1 review questions and correc
  • pharmacology study of drugs and interactions with
  • pharamacotherapeutics provide maximum benefits wi

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  • NURS 219

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NUR 219 - Patho Exam 1 Review
Questions and Correct Answers
Pharmacology ✅study of drugs and interactions with living systems

Pharamacotherapeutics ✅provide maximum benefits with minimum harm
-medical use of drugs

Pharmacology clinical ✅study of drugs on people

What is a drug? ✅any chemical that can affect living process
-all chemicals are drugs

What is an ideal drug? ✅1. Effective - does it work?
2. safety - cannot produce harmful effects
3. selectivity - does it work for the response in which it is given
4. predictability
5. Ease of administration
6. freedom from drug interactions
7. low cost
8. chemically stable
9. simple generic name

What might determine a drug response? ✅1. dose
2. route
3. timing
4. patient adherence
5. errors
6. body weight / composition
7. age
8. gender
9. pathophysiology
10. race
11. tolerance
12. genetics
13. variability in absorption

Pharamacodynamics ✅impact of drugs on body

3 types of drug names ✅1. chemical (complex)
2. Generic (only one, less complex)
3. trade (what it is marketed as)

, Reye's syndrome ✅caused by children taking ASA (aspirin) that causes brain and liver
damage
-it is most common in kids who have chicken pox or flu

What to know before you administer a drug? ✅1. right patient
2. right drug
3. right dose
4. right time
5. right route of administration
6. right documentation
7. patient has right to education
8. patient has right to refuse

Nurses Responsibility for Drugs ✅-understand basic mechanisms of Action (MOA)
-know in advance drug responses
-be last barrier against medication error
-provide education

pharmacokinetics ✅how drugs move through the body

Process of pharmacokinetics ✅1. absorption
2. distribution
3. metabolism
4. excretion

Tell me about Absorption ✅-drugs have to go across the cellular membrane
-have to be fat/lipid soluble to move across cell

describe how most drugs get absorbed? ✅-direct penetration of membrane
-passage of channel or pores (small compounds)
-must be lipid soluble
-most drugs lack transport mechanisms

Molecules that cannot penetrate cellular membrane ✅-polar : no net charge
-ionized : net charge is + or -

pH impact movement for drugs ✅-many drugs are weak acids or bases
-acids ionize in alkaline environment
-bases ionize in acidic environments
-pH gradient on 2 sides of membrane so acidic drugs will accumulate on alkaline side
and basic drugs will accumulate on acidic side

What do you have to do for basic and acidic drugs to get through the stomach? ✅-
basic drugs has to be coated so it can go through the stomach (acidic)

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